Cystatin and Early AKI Detection Contrast Induced Acute Kidney Injury

Last updated: September 25, 2025
Sponsor: BayCare Health System
Overall Status: Active - Recruiting

Phase

N/A

Condition

Kidney Disease

Renal Failure

Kidney Failure

Treatment

N/A

Clinical Study ID

NCT07197957
Cystatin & Early AKI Detection
  • Ages > 18
  • All Genders

Study Summary

To determine the clinical utility of serum cystatin C in early detection of acute kidney injury (AKI).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Subjects ages 18 years and above

  • Inpatients with CKD (Figure 1)

  • Order for CT imaging study or coronary angiography with isohexol Omnipaque) contrastmedia.

  • Pre and post contrast available

  • All races and ethnicity of patients are eligible. We expect to analyze approximatelyequal number of men and women in this study.

Exclusion

Exclusion Criteria:

  • Preexisting dialysis

  • Patients under the age of 18 years

  • Pregnancy

  • Incarcerated individuals

  • Patients with impaired cognition and unable to follow consent procedures

  • Recent exposure to CM (within 2 days before/after procedure)

  • Cardiac shock

  • Medications that affect biomarkers, including corticosteroids,lfamethoxazoletrimethoprim

Study Design

Total Participants: 100
Study Start date:
March 11, 2025
Estimated Completion Date:
February 28, 2027

Study Description

The primary objective of this study is to evaluate the clinical utility of Cystatin C in early detection of contrast-induced AKI.

To evaluate the effect of patient characteristics in the Cystatin C based GFR estimation in comparison to Cr based estimation.

Connect with a study center

  • Morton Plant Hospital

    Clearwater 4151316, Florida 4155751 33756
    United States

    Active - Recruiting

  • Morton Plant North Bay Hospital

    New Port Richey 4165869, Florida 4155751 34652
    United States

    Active - Recruiting

  • Mease Countryside Hospital

    Safety Harbor 4170797, Florida 4155751 34695
    United States

    Active - Recruiting

  • St. Anthony's Hospital

    St. Petersburg 4171563, Florida 4155751 33705
    United States

    Active - Recruiting

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