A Study Evaluating TRIV-509 in Atopic Dermatitis

Last updated: April 24, 2026
Sponsor: Triveni Bio
Overall Status: Active - Not Recruiting

Phase

2

Condition

Dermatitis, Atopic

Atopic Dermatitis

Eczema (Atopic Dermatitis)

Treatment

Placebo

TRIV-509

Clinical Study ID

NCT07167758
509-101
  • Ages 18-75
  • All Genders

Study Summary

The goal of this interventional study is to learn if TRIV-509 works to treat moderate to severe atopic dermatitis in adults. It will also evaluate the safety of TRIV-509.

Participants will receive 4 doses of the study intervention that they are randomized to (TRIV-509 or placebo), and at Week 16 will cross over and receive 4 doses of the other study intervention.

The study duration for individual participants is up to 57 weeks, including a Screening period of up to 30 days.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Has Atopic Dermatitis.

  • Has moderate to severe, active and symptomatic AD

Exclusion

Exclusion Criteria:

  • Severe or uncontrolled medical conditions.

  • Use of topical treatments, phototherapy, systemic immunosuppressives orimmunomodulatory therapies, or immunomodulatory biologics, within stated washoutperiods.

Study Design

Total Participants: 95
Treatment Group(s): 2
Primary Treatment: Placebo
Phase: 2
Study Start date:
August 26, 2025
Estimated Completion Date:
June 30, 2027

Connect with a study center

  • Triveni Bio Site #40

    Sevlievo, Gabrovo 5400
    Bulgaria

    Site Not Available

  • Triveni Bio Site #40

    Sevlievo 727337, Gabrovo 864552 5400
    Bulgaria

    Site Not Available

  • Triveni Bio Site #35

    Sofia, Sofia-Grad 1407
    Bulgaria

    Active - Recruiting

  • Triveni Bio Site #36

    Sofia, Sofia-Grad 1606
    Bulgaria

    Active - Recruiting

  • Triveni Bio Site #35

    Sofia 727011, Sofia-Grad 731061 1407
    Bulgaria

    Site Not Available

  • Triveni Bio Site #36

    Sofia 727011, Sofia-Grad 731061 1606
    Bulgaria

    Active - Recruiting

  • Triveni Bio Site #32

    Lovech, 5500
    Bulgaria

    Site Not Available

  • Triveni Bio Site #32

    Lovech 729559, 5500
    Bulgaria

    Site Not Available

  • Triveni Bio Site #38

    Pleven, 5800
    Bulgaria

    Site Not Available

  • Triveni Bio Site #38

    Pleven 728203, 5800
    Bulgaria

    Site Not Available

  • Triveni Bio Site #39

    Sofia, 1172
    Bulgaria

    Site Not Available

  • Triveni Bio Site #39

    Sofia 727011, 1172
    Bulgaria

    Active - Recruiting

  • Triveni Bio Site #13

    Ajax, Ontario L1S 7K8
    Canada

    Site Not Available

  • Triveni Bio Site #17

    Newmarket, Ontario L3Y 5G8
    Canada

    Site Not Available

  • Triveni Bio Site #12

    Niagara Falls, Ontario L2H 1H5
    Canada

    Site Not Available

  • Triveni Bio Site #15

    North York, Ontario M2N 3A6
    Canada

    Site Not Available

  • Triveni Bio Site #19

    Ottawa, Ontario K1H 1E4
    Canada

    Site Not Available

  • Triveni Bio Site #13

    Ajax 5882873, Ontario 6093943 L1S 7K8
    Canada

    Site Not Available

  • Triveni Bio Site #17

    Newmarket 6087701, Ontario 6093943 L3Y 5G8
    Canada

    Site Not Available

  • Triveni Bio Site #12

    Niagara Falls 6087892, Ontario 6093943 L2H 1H5
    Canada

    Site Not Available

  • Triveni Bio Site #19

    Ottawa 6094817, Ontario 6093943 K1H 1E4
    Canada

    Site Not Available

  • Triveni Bio Site #22

    Ostrava, 70200
    Czechia

    Site Not Available

  • Triveni Bio Site #22

    Ostrava 3068799, 70200
    Czechia

    Site Not Available

  • Triveni Bio Site #31

    Pardubice, 530 02
    Czechia

    Site Not Available

  • Triveni Bio Site #31

    Pardubice 3068582, 530 02
    Czechia

    Site Not Available

  • Triveni Bio Site #21

    Prague, 11000
    Czechia

    Site Not Available

  • Triveni Bio Site #23

    Prague, 15000
    Czechia

    Site Not Available

  • Triveni Bio Site #37

    Prague, 13000
    Czechia

    Site Not Available

  • Triveni Bio Site #21

    Prague 3067696, 11000
    Czechia

    Active - Recruiting

  • Triveni Bio Site #23

    Prague 3067696, 15000
    Czechia

    Active - Recruiting

  • Triveni Bio Site #37

    Prague 3067696, 13000
    Czechia

    Site Not Available

  • Triveni Bio Site #34

    Budapest, 1066
    Hungary

    Site Not Available

  • Triveni Bio Site #41

    Budapest, 1033
    Hungary

    Site Not Available

  • Triveni Bio Site #34

    Budapest 3054643, 1066
    Hungary

    Site Not Available

  • Triveni Bio Site #41

    Budapest 3054643, 1033
    Hungary

    Active - Recruiting

  • Triveni Bio Site #43

    Debrecen, 4032
    Hungary

    Site Not Available

  • Triveni Bio Site #33

    Wroclaw, Lower Silesian Voivodeship 51-604
    Poland

    Site Not Available

  • Triveni Bio Site #33

    Wroclaw 3081368, Lower Silesian Voivodeship 3337492 51-604
    Poland

    Site Not Available

  • Triveni Bio Site #28

    Warsaw, Masovian Voivodeship 00-872
    Poland

    Site Not Available

  • Triveni Bio Site #28

    Warsaw 756135, Masovian Voivodeship 858787 00-872
    Poland

    Site Not Available

  • Triveni Bio Site #24

    Chorzów, Silesian Voivodeship 41-500
    Poland

    Site Not Available

  • Triveni Bio Site #25

    Katowice, Silesian Voivodeship 4-600
    Poland

    Site Not Available

  • Triveni Bio Site #27

    Katowice, Silesian Voivodeship 40-611
    Poland

    Site Not Available

  • Triveni Bio Site #24

    Chorzów 3101619, Silesian Voivodeship 3337497 41-500
    Poland

    Site Not Available

  • Triveni Bio Site #25

    Katowice 3096472, Silesian Voivodeship 3337497 4-600
    Poland

    Site Not Available

  • Triveni Bio Site #27

    Katowice 3096472, Silesian Voivodeship 3337497 40-611
    Poland

    Active - Recruiting

  • Triveni Bio Site #26

    Poznan, Wielkopolska 61-731
    Poland

    Site Not Available

  • Triveni Bio Site #30

    Poznan, Wielkopolska 60-309
    Poland

    Site Not Available

  • Triveni Bio Site #26

    Poznan 3088171, Wielkopolska 61-731
    Poland

    Active - Recruiting

  • Triveni Bio Site #30

    Poznan 3088171, Wielkopolska 60-309
    Poland

    Site Not Available

  • Triveni Bio Site #29

    Sosnowiec, 41-200
    Poland

    Site Not Available

  • Triveni Bio Site #29

    Sosnowiec 3085128, 41-200
    Poland

    Site Not Available

  • Triveni Bio Site #42

    Wroclaw, 54-239
    Poland

    Active - Recruiting

  • Triveni Bio Site #18

    Kyiv, 01135
    Ukraine

    Site Not Available

  • Triveni Bio Site #18

    Kyiv 703448, 01135
    Ukraine

    Site Not Available

  • Triveni Bio Site #11

    Fountain Valley, California 17271
    United States

    Site Not Available

  • Triveni Bio Site #4

    San Diego, California 92123
    United States

    Site Not Available

  • Triveni Bio Site #11

    Fountain Valley 5350207, California 5332921 17271
    United States

    Site Not Available

  • Triveni Bio Site #4

    San Diego 5391811, California 5332921 92123
    United States

    Site Not Available

  • Triveni Bio Site #44

    New Haven, Connecticut 06519
    United States

    Site Not Available

  • Triveni Bio Site #3

    Miami, Florida 33016
    United States

    Site Not Available

  • Triveni Bio Site #7

    Tampa, Florida 33607
    United States

    Site Not Available

  • Triveni Bio Site #9

    Tampa, Florida 33609
    United States

    Active - Recruiting

  • Triveni Bio Site #3

    Miami 4164138, Florida 4155751 33016
    United States

    Site Not Available

  • Triveni Bio Site #7

    Tampa 4174757, Florida 4155751 33607
    United States

    Active - Recruiting

  • Triveni Bio Site #9

    Tampa 4174757, Florida 4155751 33609
    United States

    Site Not Available

  • Triveni Bio Site #6

    Indianapolis, Indiana 46250
    United States

    Site Not Available

  • Triveni Bio Site #10

    South Bend, Indiana 46617
    United States

    Site Not Available

  • Triveni Bio Site #6

    Indianapolis 4259418, Indiana 4921868 46250
    United States

    Site Not Available

  • Triveni Bio Site #10

    South Bend 4926563, Indiana 4921868 46617
    United States

    Site Not Available

  • Triveni Bio Site #1

    Camp Hill, Pennsylvania 17011
    United States

    Site Not Available

  • Triveni Bio Site #20

    Pittsburgh, Pennsylvania 15213
    United States

    Site Not Available

  • Triveni Bio Site #1

    Camp Hill 5182928, Pennsylvania 6254927 17011
    United States

    Site Not Available

  • Triveni Bio Site #20

    Pittsburgh 5206379, Pennsylvania 6254927 15213
    United States

    Site Not Available

  • Triveni Bio Site #16

    Bellaire, Texas 77401
    United States

    Site Not Available

  • Triveni Bio Site #2

    Dallas, Texas 75254
    United States

    Active - Recruiting

  • Triveni Bio Site #5

    Dallas, Texas 75230
    United States

    Site Not Available

  • Triveni Bio Site #16

    Bellaire 4673353, Texas 4736286 77401
    United States

    Site Not Available

  • Triveni Bio Site #2

    Dallas 4684888, Texas 4736286 75254
    United States

    Active - Recruiting

  • Triveni Bio Site #5

    Dallas 4684888, Texas 4736286 75230
    United States

    Site Not Available

  • Triveni Bio Site #14

    Springville, Utah 84663
    United States

    Site Not Available

  • Triveni Bio Site #14

    Springville 5781993, Utah 5549030 84663
    United States

    Site Not Available

  • Triveni Bio Site #8

    Spokane, Washington 99202
    United States

    Site Not Available

  • Triveni Bio Site #8

    Spokane 5811696, Washington 5815135 99202
    United States

    Site Not Available

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