Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China

Phase

N/A

Condition

Peritoneal Cancer

Liver Disease

Treatment

contrast-enhanced ultrasound examination

SonoVue®

Clinical Study ID

NCT07113808

JiYe

Ages 29-18
All Genders

Study Summary

The goal of this clinical trial is to evaluate the application of intravenous contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses. The main questions it aims to answer are:

Is intravenous contrast-enhanced ultrasound helpful for the diagnosis of intra-abdominal diseases in children?
What medical problems do participants have when participating in intravenous contrast-enhanced ultrasound examination?
How can ultrasound doctors conduct intravenous contrast-enhanced ultrasound examinations in a standardized manner? Researchers will performing intravenous contrast-enhanced ultrasound examinations on participants and collecting research subjects to establish a multicenter clinical data database.

Participants will:

Perform abdominal ultrasound examination to assess the condition.
At least conduct one intravenous contrast-enhanced ultrasound examination. Based on the result of the contrast examination, decide whether to conduct another examination.
Keep a diary of their symptoms and therapeutic process in 30 days.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Age 29 days to 18 years old;
The clinical diagnosis was abdominal space-occupying lesions, blunt abdominaltrauma, ascites of unknown cause, and children with suspected abdominal disease butother examinations could not identify the cause.

Exclusion

Exclusion Criteria:

Allergic to sulfur hexafluoride or other components;
Heart disease with right-to-left shunt/severe pulmonary hypertension /uncontrolledsystemic hypertension/respiratory failure/heart failure/severe arrhythmia;
Electrocardiogram, echocardiography or clinical manifestations of myocardialischemia;
Patients with severe blood system diseases or infectious diseases;
Hypercoagulable state and recent history of thrombosis;
Severe hepatic and renal insufficiency;
Patients with respiratory tract infection or congenital respiratory malformation.

Study Design