Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes

Last updated: May 12, 2025
Sponsor: First Affiliated Hospital of Fujian Medical University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Prostate Cancer

Urologic Cancer

Prostate Cancer, Early, Recurrent

Treatment

conventional Robotic-assisted radical prostatectomy group

Improved Robotic-assisted radical prostatectomy group

Clinical Study ID

NCT06977906
MRCTA,ECFAH of FMU [2025]546
  • Male

Study Summary

This study is a prospective, single-center clinical trial. It aims to establish an improved robotic-assisted radical prostatectomy for treating locally advanced prostate cancer. The technique evaluates the impact of preserving the anterior peritoneum of the bladder on postoperative bladder descent and urinary control recovery. A retrospective analysis compares this modified approach with traditional anterior approach surgery, assessing differences in oncological outcomes, early functional recovery, and postoperative complication rates. The goal is to provide new theoretical foundations and technical support for the prevention and treatment of postoperative urinary incontinence.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. prostate biopsy and clinical confirmation of high-risk prostate cancer (PSA > 20ng/mL, Gleason score ≥ 8, or cT stage ≥ T2c) followed by robotic-assisted radicalprostatectomy

  2. multiparametric MRI (mpMRI) with a 3.0 T scanner for prostate or pelvic scansperformed within 30 days before the operation at our center

  3. Eastern Cooperative Oncology Group (ECOG) performance status score between 0 and 1

  4. Complete clinical and prostate biopsy pathological data.

  5. General health is good, with no infections, autoimmune diseases, hematologicdisorders, or other malignancies.

Exclusion

Exclusion Criteria:

  1. Presence of surgical contraindications.

  2. refusal of enhanced mpMRI imaging.

Study Design

Total Participants: 300
Treatment Group(s): 2
Primary Treatment: conventional Robotic-assisted radical prostatectomy group
Phase:
Study Start date:
January 01, 2024
Estimated Completion Date:
January 01, 2027

Connect with a study center

  • first hospital affiliated of Fujian medical university

    Fuzhou, Fujian 350005
    China

    Active - Recruiting

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