Comparison of Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty Level in Individuals With Esophageal Atresia and Healthy Individuals

Last updated: May 9, 2025
Sponsor: Hacettepe University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Esophageal Disorders

Treatment

No intervention

Clinical Study ID

NCT06975982
FTREK24/98
  • Ages 6-18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Esophageal atresia is the most common congenital anomaly of the esophagus and is caused by abnormal development of the esophagus during intrauterine life. In children with esophageal atresia, structural abnormalities due to congenital anomalies and tracheoesophageal fistula, tracheomalacia, respiratory problems, recurrent respiratory tract infections, structural abnormalities, surgical interventions for repair and treatment, and decreased physical activity levels may negatively affect pulmonary function, effective coughing, muscle strength, exercise capacity, posture, motor function, and quality of life. This study aims to compare physical characteristics, body composition, pulmonary function and muscle strength, peak cough flow, posture assessment, peripheral muscle strength test, motor function, exercise capacity, physical activity level, fatigue, frailty and quality of life between children with esophageal atresia and their healthy peers.

Eligibility Criteria

Inclusion

Esophageal atresia group

Inclusion Criteria:

  • Children with esophageal atresia who are willing to participate in the study

  • Being between the ages of 6-18,

  • Being able to cooperate with the assessments

Exclusion

Exclusion Criteria:

  • Being unable to cooperate with the assessments,

  • Having an orthopedic, neurological or cardiovascular problem that may affect theassessments,

  • Having a lung infection or upper respiratory tract infection in the last four weeks,

  • Being an active smoker,

  • Not being willing to participate in the study,

Control group

Inclusion Criteria:

  • Being between the ages of 6-18,

  • Being willing to cooperate with the tests to be performed,

  • Being willing to participate in the study.

Exclusion Criteria:

  • Having a musculoskeletal problem that may affect exercise performance,

  • Having any known chronic disease,

  • Having a lung infection or upper respiratory tract infection in the last four weeks,

  • Being an active smoker,

  • Not willing to participate in the study.

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: No intervention
Phase:
Study Start date:
October 24, 2024
Estimated Completion Date:
October 24, 2027

Connect with a study center

  • Hacettepe University Faculty of Physical Therapy and Rehabilitation

    Ankara, 06100
    Turkey

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.