Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients

Last updated: December 18, 2025
Sponsor: Centre Hospitalier Régional d'Orléans
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

sitting out of bed in an arm-chair position

Clinical Study ID

NCT06973746
CHUO-2024-17
  • Ages > 18
  • All Genders

Study Summary

Chair positioning is one of a series of early mobilization techniques. At present, this technique, which involves moving a patient out of the resuscitation bed, can be performed passively or actively. It does not constitute a rehabilitative act as such, but it is considered in common paradigms as a technique to improve "the patient's breathing and strength".

However, recommendations issued in 2013 by the Society of intensive care physiotherapy and the society "Société de réanimation de langue française (SRLF)", reveal that this chair position cannot be recommended with a high grade.

The aim of the investigators is therefore to break down this early mobilization process in intensive care, to find out whether the armchair is an indispensable tool for improving functional and muscular processes.

The research hypothesis is therefore as follows:

"Early armchairing of the resuscitation patient, improves functional recovery compared to a conservative positioning strategy (sitting in bed)."

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patient > 18 years old

  2. Patient on invasive mechanical ventilation for more than 24 hours

  3. Patient in recovery phase with a RASS score greater than "-3" for more than 12 hours

  4. Stay expected to last 48 hours

  5. Patient has never been placed in a chair during this hospitalization in intensivecare.

  6. Fragility score < 6, during the month preceding admission to intensive care

  7. Patient (or support person/relative if patient is unable to participate) who hasagreed to take part in the study.

Exclusion

Exclusion Criteria:

  1. Patient with an absolute and non-resolving contraindication to chair positioning

  2. Fracture or orthopedic disorder contraindicating mobilization out of bed

  3. Obesity with body mass index greater than 45 kg/cm2

  4. Sacral eschar stage greater than 2

  5. Patient using a wheelchair for mobility (i.e. paraplegic patient or patient withprogressive neurological pathology).

  6. Patient treated with veno-venous or veno-arterial ECMO at the time of screening.

  7. Moribund patient

  8. Encephalic death

  9. Acute polyradiculoneuritis (Guillain-Barré syndrome)

  10. Myasthenia

  11. Patient treated by continuous hemodialysis or hemofiltration for more than 72 hoursfollowing the onset of awakening.

  12. Complete transmetatarsal or higher amputation of one or both lower limbs.

  13. Protected person (under guardianship or curatorship)

  14. Person under court protection

  15. Person not affiliated to a social security scheme

  16. Pregnant or breast-feeding woman

  17. Patient already included in the study

  18. Patient taking part in an interventional clinical study, the aim of which is to showan improvement in functional level on discharge from the intensive care unit orwhich focuses on the theme of early rehabilitation in the intensive care unit.

Study Design

Total Participants: 150
Treatment Group(s): 1
Primary Treatment: sitting out of bed in an arm-chair position
Phase:
Study Start date:
July 04, 2025
Estimated Completion Date:
January 31, 2028

Connect with a study center

  • Centre Hospitalier Universitaire d'Orléans

    Orléans, Centre Val De Loire 45067
    France

    Site Not Available

  • Centre Hospitalier Universitaire d'Orléans

    Orléans 2989317, Centre-Val de Loire 3027939 45067
    France

    Active - Recruiting

  • Hopital Nord Franche Comte

    Belfort,
    France

    Site Not Available

  • Hopital Nord Franche Comte

    Belfort 3033791,
    France

    Active - Recruiting

  • CHU Clermont Ferrand

    Clermont-Ferrand,
    France

    Site Not Available

  • CHU Clermont Ferrand

    Clermont-Ferrand 3024635,
    France

    Active - Recruiting

  • CH de DAX

    Dax, 40100
    France

    Site Not Available

  • CH de DAX

    Dax 3021670, 40100
    France

    Site Not Available

  • CHU de DIJON

    Dijon,
    France

    Site Not Available

  • CHU de DIJON

    Dijon 3021372,
    France

    Active - Recruiting

  • CH Chartres

    Le Coudray, 28630
    France

    Site Not Available

  • CH Chartres

    Le Coudray 3004471, 28630
    France

    Active - Recruiting

  • Ch Du Mans

    Le Mans, 72037
    France

    Site Not Available

  • Ch Du Mans

    Le Mans 3003603, 72037
    France

    Active - Recruiting

  • CHI Mont de Marsan

    Mont-de-Marsan, 40012
    France

    Site Not Available

  • CHI Mont de Marsan

    Mont-de-Marsan 2992771, 40012
    France

    Active - Recruiting

  • CH de Saint-Lô

    Saint-Lô 2978758,
    France

    Site Not Available

  • Hopital Foch

    Suresnes,
    France

    Site Not Available

  • Hopital Foch

    Suresnes 2973675,
    France

    Site Not Available

  • CHRU de TOURS

    Tours,
    France

    Site Not Available

  • CHRU de TOURS

    Tours 2972191,
    France

    Active - Recruiting

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