Quality of Recovery in Laparoscopic Sleeve Gastrectomy Using Dexmedetomidine Infusion Versus Laparoscopic TAP Block in Combination With Paragastric Neural Block

Last updated: May 6, 2025
Sponsor: Alexandria University
Overall Status: Active - Recruiting

Phase

2/3

Condition

N/A

Treatment

Laparoscopic Transversus Abdominis Plane (LTAP) block

Paragastric neural block

Dexmedetomidine infusion

Clinical Study ID

NCT06970626
16/462
  • Ages 20-60
  • All Genders

Study Summary

The goal of this clinical trial is to learn which is better, combining Dexmedetomidine infusion and paragastric neural block or combining laparoscopic TAP block and paragastric neural block to enhance recovery after laparoscopic sleeve gastrectomy.

The main questions it aims to answer are:

Will using paragastric neural block (PGNB) combined with dexmedetomidine infusion give better recovery or using PGNB combined with laparoscopic transversus abdominis plane (LTAP) block in patients undergoing laparoscopic sleeve gastrectomy.

This will be assessed by:

Recording how much opioids were consumed by the patients Hemodynamic stability of the enrolled patients Pain scores as given by the patient The quality of postoperative patient recovery How many patients encountered nausea or vomiting

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. American Society of Anesthesiologists (ASA) physical status II- III

  2. BMI 35- 50 kg/m2

Exclusion

Exclusion Criteria:

  1. Significant hepatic, renal, neuromuscular, or cardiac impairments

  2. Extreme obesity (BMI > 50 kg/m2)

  3. Patients on current opioid medication

  4. Allergies to dexmedetomidine or bupivacaine

Study Design

Total Participants: 60
Treatment Group(s): 3
Primary Treatment: Laparoscopic Transversus Abdominis Plane (LTAP) block
Phase: 2/3
Study Start date:
April 03, 2025
Estimated Completion Date:
June 20, 2025

Connect with a study center

  • Alexandria Main University Hospital

    Alexandria,
    Egypt

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.