Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)

Last updated: May 5, 2025
Sponsor: İstanbul Yeni Yüzyıl Üniversitesi
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pain

Open Heart Surgery

Heart Transplantation

Treatment

Local wound infiltration with bupivacaine

Ultrasound-guided serratus anterior plane block and serratus-intercostal interfascial plane block with bupivacaine

Clinical Study ID

NCT06968065
2024101338
  • Ages 18-75
  • All Genders

Study Summary

This randomized, prospective, single-blinded study aims to compare the efficacy of ultrasound-guided serratus anterior plane (SAP) block combined with serratus-intercostal interfascial plane (SIP) block versus local wound infiltration (LWI) for postoperative analgesia in patients undergoing minimally invasive cardiac surgery (MICS). The primary outcome is total perioperative and postoperative opioid consumption. Secondary outcomes include postoperative pain scores (NRS), opioid-related side effects, block-related complications, and ICU stay duration.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-75 years

  • Undergoing MICS with left-sided 4th-5th intercostal incision

  • ASA I-III

  • Informed consent provided

Exclusion

Exclusion Criteria:

  • Coagulopathy or on anticoagulants

  • Allergy to local anesthetics or opioids

  • Local infection at block site

  • Pregnancy or lactation

  • Bilateral thoracic incisions

  • Refusal to participate

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: Local wound infiltration with bupivacaine
Phase:
Study Start date:
October 17, 2024
Estimated Completion Date:
June 30, 2025

Study Description

Minimally invasive cardiac surgery (MICS) has gained popularity due to reduced surgical trauma and faster recovery. However, postoperative pain management remains a challenge. This study evaluates the analgesic effectiveness of combining two interfascial plane blocks-SAP and SIP-under ultrasound guidance, compared to traditional local wound infiltration. A total of 60 patients scheduled for MICS with cardiopulmonary bypass will be randomized into two groups (SAP+SIP vs LWI). Pain scores, opioid usage, and complications will be recorded at predetermined intervals up to 72 hours postoperatively.

Connect with a study center

  • Kolan International Hospital

    Istanbul,
    Turkey

    Active - Recruiting

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