PRIDE III Prison Interventions and HIV Prevention Collaboration

Last updated: May 8, 2025
Sponsor: Yale University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hiv

Drug Use

Treatment

Opioid Agonist Therapy

Clinical Study ID

NCT06962033
2000037393
2R01DA029910-11A1
  • Ages > 18
  • All Genders

Study Summary

The primary objective of this research project is to identify barriers to scale-up of Opioid Agonist Therapy (OAT) in the justice systems (prisons and probation) in Tajikistan, Kyrgyzstan, Moldova, and Georgia, and establish a NIATx learning collaborative to scale-up OAT, and analyze scale-up utilizing latent class growth analyses in people who inject drugs (PWID).

Eligibility Criteria

Inclusion

Inclusion Criteria:

Aim 1:

  1. Quantitative surveys for prison OAT providers

  • Being 18 years or older

  • Being currently assigned and working as a probation OAT provider for aprobation site

  1. ECHO procedures

Aim 2:

  1. Quantitative surveys for people in probation

  • Being 18 years or older

  • Screen yes to opioid injection on the online screener questionnaire

  • Currently in probation

  1. Quantitative surveys for probation and prison officers

  • Being 18 years or older

  • Being currently assigned and working as a probation or prison officer at aprobation site

  1. Focus Groups (People in probation)

  • Being 18 years or older

  • Screen yes to opioid injection criteria on the online screener

  • Currently in probation

  1. Focus Groups (Probation and prison officers)

  • Being 18 years or older

  • Being currently assigned and working as a probation or prison officer at aprobation

  • Has more than 3 months of field experience

  • Works at a probation site within 25 kilometers of an OAT site

Exclusion

Exclusion Criteria:

Study Design

Total Participants: 300
Treatment Group(s): 1
Primary Treatment: Opioid Agonist Therapy
Phase:
Study Start date:
November 05, 2024
Estimated Completion Date:
December 31, 2028

Study Description

Aim 1 consists of the development of NIATx learning collaboratives with prison OAT providers (addiction care specialists or primary care doctors). This aim is an implementation science aim involving the collection of OAT scale-up data from each country's national OAT database, as well as administration of survey to prison narcologists every 6 months.

Aim 2 consists of the development of NIATx learning collaboratives with probation and prison officers in Kyrgyzstan, Tajikistan, Moldova, and Georgia. Investigators will collect OAT scale-up data from each member country's national OAT database, and administer a survey to probation officers every 6 months. Investigators will also observe and interview probation clients and staff using ethnographic methods.

Connect with a study center

  • Alternative Georgia

    Tbilisi,
    Georgia

    Active - Recruiting

  • AIDS Foundation East-West (AFEW)

    Bishkek,
    Kyrgyzstan

    Active - Recruiting

  • NGO AFI

    Chisinau,
    Moldova, Republic of

    Active - Recruiting

  • Institute for International Health and Education (IIHE)

    Dushanbe,
    Tajikistan

    Active - Recruiting

  • Yale University

    New Haven, Connecticut 06520
    United States

    Site Not Available

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