Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

Phase

N/A

Condition

Throat And Tonsil Infections

Treatment

oral dexamethasone

intramuscular dexamethasone

Clinical Study ID

NCT06959407

410/DME/KMC

Ages 2-12
All Genders

Study Summary

Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness. It mainly affects children aged 6 months to 12 years, peaking at around 2 years. Most cases are mild and self-limiting. Emergency treatments include cool mist, nebulized epinephrine, and steroids. Steroid therapy, particularly dexamethasone (oral or intramuscular), is commonly used, with recent studies suggesting intramuscular dexamethasone may be more effective. However, most research has focused on hospitalized patients, and there is a lack of local data for mild cases. This study aims to address that gap and improve patient counseling and future research

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patient age 2 to 12 years
Both genders
Diagnosed with croup as operational definitions

Exclusion

Exclusion Criteria:

Patients with chronic pulmonary disease like tuberculosis,
Allergy or contraindication of corticosteroid (history of tuberous sclerosis,history of varicella infection during the past three weeks), to corticosteroids,
history of corticosteroid administration during the last four weeks,
foreign body
patients with immunodeficiency disorder

Study Design