The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study

Last updated: April 26, 2025
Sponsor: The Second Affiliated Hospital of Chongqing Medical University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Chronic Pain

Acute Pain

Pain

Treatment

Arterial blood

Peripheral venous blood

Clinical Study ID

NCT06957158
Serum calcium levels and pain
  • Ages 18-70
  • All Genders

Study Summary

This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Aged 18-70 years old

  • American Society of Anesthesiologists Classification I-III

  • Patients undergoing elective abdominal surgery under general anesthesia

  • Patients participate voluntarily and sign an informed consent form

Exclusion

Exclusion Criteria:

  • Patients with a history of severe disease

  • Patients with chronic preoperative pain and/or long-term analgesic use

  • Patients with hearing disorders or verbal communication difficulties

  • Patients with psychiatric disorders or cognitive dysfunction

  • Patients requiring mechanical ventilation or ICU admission after surgery

  • Patients with a history of substance or alcohol abuse Patients who could notcooperate with the study for any reason

Study Design

Total Participants: 350
Treatment Group(s): 2
Primary Treatment: Arterial blood
Phase:
Study Start date:
May 01, 2025
Estimated Completion Date:
December 31, 2025

Study Description

This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.

Connect with a study center

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing 400010
    China

    Active - Recruiting

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