ESCAPE : Evaluation of Spinal Conservation by Endoscopic Procedures to Avoid Fusion

Last updated: April 22, 2025
Sponsor: University Hospital, Bordeaux
Overall Status: Active - Recruiting

Phase

N/A

Condition

Ankylosing Spondylitis

Spinal Stenosis

Spondylolisthesis

Treatment

N/A

Clinical Study ID

NCT06950853
CHUBX 2023/60
  • Ages > 18
  • All Genders

Study Summary

The recent development and expansion of endoscopic surgery has made it possible to offer an alternative to this therapeutic escalation. This method allows decompression procedures to be performed using optimized and minimally destructive surgical approaches, which contributes to preserving the physiological function of the lumbar spine and in particular its stability.

The main hypothesis of the research is that the use of endoscopic techniques for decompression of the lumbar spine allows a reduction in the indication for lumbar arthrodesis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient ≥ 18 years old

  • Patient consulting for a medical reason involving a spinal pathology in theinvestigating center :

Syndrome adjacent to an old lumbar arthrodesis defined on preoperative radiographs by an antero-posterior translation > 3 mm, segmental kyphosis > 10° or a disc height reduced by more than 50%, or on preoperative MRI by central stenosis of grade C or D of the Schizas classification or a herniated disc Grade 1 or 2 degenerative spondylolisthesis, i.e. with slippage less than 50% of the depth of the underlying vertebral body.

Lumbar stenosis complicating lumbar scoliosis defined by a deformation with rotation of the vertebral bodies on a frontal radiograph (absence of centering of the spinous process between the two pedicles of the vertebra concerned) and a Cobb angle greater than 20° or a rotational dislocation .

  • Indication for spinal surgery by endoscopy

Exclusion

Exclusion Criteria:

  • Patient under guardianship or curatorship,

  • Persons deprived of liberty by judicial or administrative decision,

  • Persons undergoing psychiatric treatment under duress requiring the consent of thelegal representative

  • Persons unable to express their consent,

  • Persons under legal protection,

  • Patient not affiliated to a social protection scheme.

Study Design

Total Participants: 375
Study Start date:
February 01, 2024
Estimated Completion Date:
August 13, 2028

Connect with a study center

  • Hôpital Pellegrin, Centre Hospitalier Universitaire de Bordeaux

    Bordeaux, 33000
    France

    Active - Recruiting

  • Clinique du dos de Bordeaux -Terrefort

    Bruges, 33520
    France

    Active - Recruiting

  • CHU Lille

    Lille, 59037
    France

    Site Not Available

  • Centre orthopédique SANTY

    Lyon, 69008
    France

    Site Not Available

  • Hôpital CLAIRVAL

    Marseille, 13009
    France

    Active - Recruiting

  • CH de Narbonne

    Narbonne, 11108
    France

    Active - Recruiting

  • Centre hospitalier Privé Sainte Marie

    Osny, 95520
    France

    Site Not Available

  • Clinique du sport

    Pessac, 33600
    France

    Active - Recruiting

  • Institut locomoteur de l'Ouest-Rachi

    Saint-gregoire, 35760
    France

    Active - Recruiting

  • Cabinet Orthosud Montpellier-Clinique Saint Jean

    Saint-jean-de-vedas, 34430
    France

    Active - Recruiting

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