Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma

Last updated: April 22, 2025
Sponsor: West China Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carcinoma

Liver Disease

Liver Cancer

Treatment

postoperative adjuvant therapy

Clinical Study ID

NCT06950814
JHuang20231
  • Ages > 18
  • All Genders

Study Summary

In recent years, researchers have conducted extensive studies on adjuvant therapy following surgical resection of liver cancer, exploring its potential benefits and seeking effective treatment strategies. Given the rarity and high aggressiveness of primary hepatic sarcomatoid carcinoma, there is a lack of reliable clinical evidence on whether postoperative adjuvant therapy can benefit patients, resulting in the absence of established standard guidelines. Therefore, we conducted a single-center retrospective study to assess the potential benefits of postoperative adjuvant therapy for patients of primary hepatic sarcomatoid carcinoma.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. patients who underwent liver resection

  2. patients' postoperative paraffin pathology and immunohistochemistry results werereviewed to identify those diagnosed with PHSC

Exclusion

Exclusion Criteria:

  1. patients who received other anti-tumor treatments before surgery, such asradiofrequency ablation (RFA), transarterial chemoembolization (TACE), radiationtherapy (RT), and systemic therapy;

  2. patients diagnosed with other specific types of sarcomas;

  3. patients with concurrent other malignancies during the course of PHSC;

  4. patients who were lost to follow-up or lacked essential clinical data.

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: postoperative adjuvant therapy
Phase:
Study Start date:
April 05, 2025
Estimated Completion Date:
May 05, 2025

Connect with a study center

  • West China Hospital

    Chengdu, Sichuan 610041
    China

    Active - Recruiting

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