A PRPCT to Assess the Efficacy & Safety of Chronic Pain Rehab Training Software for Alleviating Chronic Secondary Musculoskeletal Pain

Inclusion Criteria:

• Males and females ≥18 years old.

• Average pain intensity≥4 on a 0-10 numerical rating scale (NRS) in the past 24hours.

• Be able to communicate in Chinese.

• Be able to read and write Chinese.

• Willing to comply with study procedures and restrictions.

• Willing and able to sign informed consent.

Exclusion Criteria:

• Shingles on the eyes, ears, head, face, or hands.

• Trigeminal neuralgia.

• Severe vision impairment. (Patients with clear vision wearing glasses or contactlenses are allowed)

• Severe hearing impairment.

• Disease or medical condition predisposing to nausea or dizziness, such asinsufficient blood supply to the brain, vestibular dysfunction,cholecystitis, etc.

• History of severe motion sickness.

• Injury to eyes, ears, face, or neck that impedes comfortable use of mixed reality.

• Injury or dysfunction of hands or upper limbs that impedes comfortable use of mixedreality.

• Diagnosis of cognitive impairment, epilepsy, dementia, migraines or otherneurological diseases that may prevent the use of mixed reality.

• History of mental illness, including depression, generalized anxiety disorder,schizophrenia, etc.

• Females currently pregnant.

• Current or completion of participation within 4 weeks before screening in anyinterventional clinical study

• Patients whom the investigator considers not suitable to participate in this study.