Effects of Mat and Reformer Pilates in Multiple Sclerosis

Last updated: June 10, 2025
Sponsor: Gazi University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Memory Loss

Multiple Sclerosis

Scar Tissue

Treatment

Mat Pilates

Reformer Pilates

Clinical Study ID

NCT06931522
2023 - 960
  • Ages 18-65
  • All Genders

Study Summary

Our study aims to investigate the effects of core stability-based Mat Pilates and Equipment-Based Pilates training on anticipatory postural adjustments (APA), balance, and gait in individuals with Multiple Sclerosis (MS). Participants diagnosed with MS will be randomly assigned to Mat Pilates, Equipment-Based Pilates, or a control group. Both Pilates programs will be conducted twice a week for eight weeks.

Assessments will be conducted before and after the training period. Anticipatory postural adjustments (APA) will be evaluated using electromyography (EMG) electrodes placed on the Erector Spinae and Tibialis Anterior muscles while participants take a step. Biomechanical responses related to APAs, specifically center of pressure displacement, will be measured using a force platform (Biodex® BioSway).

Core endurance will be assessed using the lateral bridge test, Modified Biering-Sorensen test, trunk flexion test, and prone bridge test, while core strength will be evaluated through sit-ups and push-ups. Balance will be measured using posturography. The Activities-Specific Balance Confidence (ABC) Scale will assess confidence in performing daily activities requiring balance. Functional mobility will be evaluated using the Timed Up and Go (TUG) test. Spatiotemporal gait parameters and variability will be analyzed with the BTS® G-WALK system. The Multiple Sclerosis Quality of Life Questionnaire (MSQOL-54) will assess quality of life.

This study is unique in that, unlike previous Pilates studies, it will be the first to examine the effects of different Pilates methods on APAs, which are crucial for both locomotor activities and postural stability in individuals with MS. Additionally, it will be the first study to evaluate two commonly used Pilates techniques in terms of their impact on balance and gait.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosis of Multiple Sclerosis by a specialist physician

  • Having a disability level between 0-4.5 according to the Expanded Disability StatusScale (EDSS)

  • Being between the ages of 18-65

  • Not having had an attack in the last 3 months

  • Mini-Mental Test score > 25

Exclusion

Exclusion Criteria:

  • Having another neurological disorder

  • Having orthopedic, cardiovascular, and pulmonary problems that may affect theresearch results

  • Having vision, hearing, and perception problems

  • Having a disease that may affect the immune system, such as infection, cancer

Study Design

Total Participants: 10
Treatment Group(s): 2
Primary Treatment: Mat Pilates
Phase:
Study Start date:
June 10, 2025
Estimated Completion Date:
September 01, 2025

Connect with a study center

  • Gazi University

    Ankara,
    Turkey

    Active - Recruiting

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