A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Last updated: April 15, 2025
Sponsor: Massachusetts General Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Schizophrenia And Schizoaffective Disorders (Pediatric)

Panic Disorders

Affective Disorders

Treatment

Resilience Training (RT)

Life Skills Training (LST)

Clinical Study ID

NCT06929442
2016P0023511
  • Ages 18-30
  • All Genders

Study Summary

This is a randomized controlled trial testing the efficacy of Resilience Training in college students with elevated transdiagnostic risk for developing a serious mental illness.

Eligibility Criteria

Inclusion

Inclusion criteria:

  1. 18-30 years old

  2. Enrolled as a first or second year student (i.e., freshman or sophomore) in anundergraduate program at the college or university where the intervention takesplace

  3. Students who endorse some psychotic experiences (Peter's et al. Delusion Inventory (PDI) score > 3)

Exclusion

Exclusion criteria:

  1. Inability to provide informed consent

  2. Not proficient in English

  3. Current self-reported Diagnostic Statistical Manual 5 (DSM-5) diagnosis with activesymptoms (such as active psychotic symptoms, current suicidality, serious activealcohol or substance use, marked deterioration in functioning over the prior month)determined by clinical interview with participant, or self-report of a psychiatricdiagnosis that necessitates close monitoring or individual therapy and/or inpatientor partial hospitalization

  4. Current enrollment in psychological or behavioral health treatment.

  5. Current use of psychotropic medications (other than stimulants) prescribed by aphysician.

  6. A diagnosis of a serious, chronic mental illness as determined by theMini-International Neuropsychiatric Interview (MINI)

Study Design

Total Participants: 192
Treatment Group(s): 2
Primary Treatment: Resilience Training (RT)
Phase:
Study Start date:
February 10, 2025
Estimated Completion Date:
June 30, 2029

Connect with a study center

  • Massachusetts General Hospital

    Charlestown, Massachusetts 02129
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.