Effect of Upper Thoracic Manipulation on Neck Pain and Selected Muscle Activities

Last updated: April 30, 2025
Sponsor: Cairo University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Chronic Pain

Neck Pain

Chronic Musculoskeletal Pain

Treatment

Upper Thoracic Manipulation

Sham Comparison

Clinical Study ID

NCT06926738
Upper thoracic manipulation
  • Ages 18-40
  • All Genders

Study Summary

This study will investigate the immediate and short-term effects of upper thoracic manipulation versus sham upper thoracic manipulation on Pain intensity, Cervical ROM, the myoelectric activity of the sternocleidomastoid muscle and upper trapezius muscle during Maximum voluntary isometric contraction.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Male and female subjects diagnosed and classified as having chronic non-specific NPwith mobility disorders based on clinical guidelines of NP:
  • Having NP for at least 3 months that may be associated with referred shoulderor upper extremity pain (Blanpied et al., 2017; Erdem et al., 2021;Puntumetakul et al., 2015).

  • Present with a limitation of cervical ROM and their pain can be provoked bysustained end-range spinal movements or positions will be included (Blanpied etal., 2017).

  • Patients present with unilateral or bilateral symptoms will be included (Blanpied et al., 2017; Yang et al., 2015).

  1. Age between 18-40 (J. Dunning & Rushton, 2009)

  2. Negative four tests of the Wainner cluster to exclude NP with radiating pain (Wainner et al., 2003).

  3. Hypomobility of at least one of the upper thoracic vertebrae (T1-T4) duringsegmental mobility assessment (Ssavedra-Hernández et al., 2011).

Exclusion

Exclusion Criteria:

  1. Subjects diagnosed as cervical radiculopathy or myelopathy (Ssavedra-Hernández etal., 2011).

  2. A history of whiplash injury, past cervical or thoracic surgery, rheumatoidarthritis, spinal fracture, heart disease, a recent significant trauma, andmeningitis (Joshi et al., 2020; Puntumetakul et al., 2015).

  3. The presence of contraindications of spinal manipulation as spinal infection andspinal osteoporosis(Ssavedra-Hernández et al., 2011).

Study Design

Total Participants: 42
Treatment Group(s): 2
Primary Treatment: Upper Thoracic Manipulation
Phase:
Study Start date:
April 15, 2025
Estimated Completion Date:
February 28, 2026

Study Description

This study will investigate the immediate and short-term effects of upper thoracic manipulation versus sham upper thoracic manipulation on Pain intensity measured by the visual analogue scale, Cervical ROM measured by CROM, the myoelectric activity of the sternocleidomastoid muscle and upper trapezius muscle during Maximum voluntary isometric contraction measured by Neuro-Soft using surface electrodes. All outcomes will be measured Pre-intervention, Immediately Post-Intervention, One-week Post-intervention, Two-week post-intervention.

Connect with a study center

  • CairoU

    Giza, 12611
    Egypt

    Active - Recruiting

  • Faculty of Physical Therapy, Cairo University

    Giza, 12611
    Egypt

    Active - Recruiting

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