Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia

Last updated: April 9, 2025
Sponsor: Institute of Hematology & Blood Diseases Hospital, China
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anemia

Red Blood Cell Disorders

Lupus

Treatment

Brain function and psychological assessment

Clinical Study ID

NCT06921980
QTJC2025011
  • Ages 18-65
  • All Genders

Study Summary

Cell therapy is an innovative treatment with significant efficacy in hematologic and certain autoimmune diseases. Although it offers potential benefits for autoimmune hemolytic anemia (AIHA), it may result in cognitive and other potential impairments, which can adversely affect patients' cognition and behavior.

Brain function and psychological assessment are essential for the early detection of potential impairments, allowing timely interventions to prevent complications and ensure patient safety. This study aims to comprehensively evaluate the physical and psychological impacts of cell therapy on AIHA patients to develop safer and more effective treatment strategies that enhance their quality of life.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosis of AIHA

  • Subjects will receive cell therapy such as CAR T-cell therapy

  • Male or female, aged 18-65 years

  • Willing and able to comply with the requirements for this study and written informedconsent

Exclusion

Exclusion Criteria:

  • History of psychiatric illness

  • History of severe brain disease

  • Subjects that the investigator believes have other reasons that make them unsuitablefor inclusion in this study

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: Brain function and psychological assessment
Phase:
Study Start date:
February 25, 2025
Estimated Completion Date:
December 31, 2026

Connect with a study center

  • Regenerative Medicine Center

    Tianjin, Tianjin
    China

    Active - Recruiting

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