Acupuncture for People Experiencing Period Loss Due to Chemotherapy

Inclusion Criteria:

• English speaking woman between the ages of 15 and 40

• History of stage I, II, or III cancer OR stage IV or unstaged hematologic malignancy (e.g. lymphoma, leukemia, myeloma) that is stable, as assessed by care team

• Premenopausal status with regular menstruation at the time of diagnosis by patientreport

• Completed cytotoxic chemotherapy within the past year

• Premenopausal status with regular menstruation at the time of diagnosis by patientreport for females ages 18 or older

• Report cessation of menses during or after chemotherapy and have not experiencedmenses recovery at the time of enrollment.

• Have reached menarche prior to therapy or during therapy for females between 15 and 17 years old

• Patient reports cessation of menses during or after chemotherapy and have notexperienced menses recovery at the time of enrollment.

• Have been without menses for at least 3 months 64 following the completion ofcytotoxic chemotherapy

• Willing to adhere to all study-related procedures, including randomization to one ofthe two possible arms: acupuncture and WLC

Exclusion Criteria:

• Had been pregnant or lactating within 3 months prior to enrollment

• History of hysterectomy or bilateral oophorectomy

• Ongoing or planned radiation or surgery within 4 months from randomization

• Use of acupuncture for menses recovery within 3 months of enrollment

• Had been or will be receiving ovarian suppression medicine, such as leuprolide (Lupron) and goserelin (Zoladex), or hormonal contraception drugs within 3 months ofenrollment or during the study period