BoTox Into the Sternocleidomastoid Muscles (SCM)

Last updated: June 3, 2025
Sponsor: Boston Medical Center
Overall Status: Active - Recruiting

Phase

4

Condition

N/A

Treatment

prabotulinumtoxinA-xvfs

Clinical Study ID

NCT06903975
H-45473
  • Ages 18-65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary slimming effect on the neck and produce a more feminine, youthful neck contour.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age eligible individual seeking a more feminine neck appearance

Exclusion

Exclusion Criteria:

  • Prior neuromodulator injections in the sternocleidomastoid muscles (SCM) within thepast year

  • Current anticoagulant use

  • Body mass index (BMI) >30

  • Anticipation of significant weight gain or loss during the study period (e.g.patients taking or planning to take within the study period a semaglutidemedication.)

  • Prior allergy to botulinum toxin A

  • Currently pregnant or breastfeeding

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: prabotulinumtoxinA-xvfs
Phase: 4
Study Start date:
May 14, 2025
Estimated Completion Date:
March 31, 2026

Study Description

The specific study objectives are to determine if:

  • the neck circumference is decreased at 4 weeks after botulinum toxin (prabotulinumtoxinA-xvfs) injection.

  • patients can appreciate a difference in their neck contour, self-confidence, and the way they perceive themselves post-injection via an aesthetics outcome and a neck perception survey.

  • injection of the botulinum toxin into the sternocleidomastoid muscle is safe to perform based on adverse events.

Connect with a study center

  • The Spiegel Center

    Newton, Massachusetts 02459
    United States

    Active - Recruiting

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