Ashwagandha Supplementation for Prevention of Muscle Damage

Last updated: April 17, 2025
Sponsor: University of Saskatchewan
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Placebo

Ashwagandha

Clinical Study ID

NCT06900569
2024_25_06
  • Ages 18-35
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Ashwagandha is an herbal supplement that has a wide range of benefits related to exercise when supplemented for about 8-12 weeks. This study aims to investigate whether short-term Ashwagandha supplementation can enhance muscle recovery following exercise by measuring muscle strength recovery, swelling, and soreness in the biceps.

Eligibility Criteria

Inclusion

Inclusion Criteria: male or female, aged 18-35y

Exclusion

  • Exclusion Criteria:

Conditions that may be affected by exercise (determined by "yes" answers to the "Get Active Questionnaire") Pregnant Breastfeeding

Allergies to:

  • Dicalcium Phosphate

  • Cellulose

  • Vegetable magnesium stearate

  • Silica

Study Design

Total Participants: 20
Treatment Group(s): 2
Primary Treatment: Placebo
Phase:
Study Start date:
March 22, 2025
Estimated Completion Date:
May 15, 2025

Study Description

The purpose of the study is to determine the effects of Ashwagandha supplementation on recovery from muscle-damaging exercise. Ten to twenty participants will be randomized to receive Ashwagandha supplementation (600 mg/d) or placebo for 10 days. On day 7, participants will perform a muscle damaging exercise session (six sets of concentric and emphasized eccentric repetitions with the biceps). Before and after exercise and at 24, 48, and 72 hours after exercise, isometric muscle strength, muscle swelling (ultrasound), and muscle soreness will be assessed. The investigators hypothesize the Ashwagandha will alleviate symptoms of muscle damage (swelling and soreness) and enhance strength recovery after a bout of muscle-damaging exercise.

Connect with a study center

  • University of Saskatchewan

    Saskatoon, Saskatchewan S7K 2X2
    Canada

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.