Phase II Clinical Study to Evaluate the Efficacy and Safety of VC005 in Adult Subjects With Mild to Moderate Atopic Dermatitis

Last updated: May 5, 2025
Sponsor: Jiangsu vcare pharmaceutical technology co., LTD
Overall Status: Active - Recruiting

Phase

2

Condition

Atopic Dermatitis

Skin Infections/disorders

Hives (Urticaria)

Treatment

VC005 groups

VC005 Placebo group

Clinical Study ID

NCT06891040
VC005-203
  • Ages > 18
  • All Genders

Study Summary

A multicenter, randomized, double-blind, vehicle controlled phase II clinical study

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Subjects fully understand this study, are able to follow the relevant procedures ofthe trial, voluntarily participate in the clinical trial, and sign the informedconsent form (ICF);

  2. The age requirement for signing the ICF is 18 years old or above, with no genderrestrictions;

  3. During screening, the diagnosis of atopic dermatitis should be met according to theHanifin-Rajka criteria;

Exclusion

Exclusion Criteria:

  1. Skin damage or abnormalities that may affect the evaluation of the administrationsite of the investigational drug;

  2. Skin diseases that are contraindicated in research or affect the evaluation of drugadministration sites, including but not limited to psoriasis, acne, and skin cancer;

  3. Suffering from autoimmune diseases other than AD, such as inflammatory bowel diseaseand rheumatoid arthritis, and the researchers believe that this disease will bedetrimental to the evaluation of this study;

  4. Current history of or presence of lymphoproliferative disorders, or signs orsymptoms suggesting possible lymphoproliferative disorders, includinglymphadenopathy or splenomegaly;

  5. Various malignant tumors, or any history of malignant tumors within the past 5 yearsprior to screening (excluding completely resected cervical carcinoma in situ, nonmetastatic squamous cell carcinoma, basal cell carcinoma, or papillary thyroidcarcinoma);

Study Design

Total Participants: 114
Treatment Group(s): 2
Primary Treatment: VC005 groups
Phase: 2
Study Start date:
April 28, 2025
Estimated Completion Date:
December 30, 2025

Connect with a study center

  • Chinese Academy of Medical Sciences Hospital of Skin Disease

    Nanjing, Jiangsu
    China

    Active - Recruiting

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