A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices: The Novel Cor-IS Technology Will Also be Evaluated

Last updated: April 28, 2025
Sponsor: Aristotle University Of Thessaloniki
Overall Status: Active - Recruiting

Phase

N/A

Condition

Myocardial Ischemia

Heart Disease

Coronary Artery Disease

Treatment

Observation group

Clinical Study ID

NCT06890013
198/31.5.2024
  • Ages 18-85
  • All Genders

Study Summary

A prospective, single-center, observational study aiming to assess the predictive role of flow mediated dilatation in acute coronary syndromes, combined with echocardiographic and biochemical indices. The novel Cor-IS technology will also be evaluated.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age > 18 years

  2. Patients hospitalized due to acute coronary syndrome (STEMI, NSTEMI)

  3. Capability of providing written informed consent

  4. Patients able to comply with the follow-up schedule of the study

Exclusion

Exclusion Criteria:

  1. Patients with acute coronary syndromes classified as MINOCA, or type II myocardialinfarction

  2. Patients with rare acute coronary syndrome types, such as spontaneous coronaryartery dissection or Takotsubo syndrome

  3. Patients with congenital heart disease

  4. Age > 85 years

  5. Patients with end stage chronic kidney disease

  6. Patients with active malignancy or autoimmune diseases which limit their survival

  7. Patients with expected survival < 1 year due to other reasons

  8. Suboptimal echocardiographic windows

  9. Inability to provide written consent

  10. Inability to comply with the follow-up schedule of the study

  11. Pregnancy

  12. Use of intravenous drugs

Study Design

Total Participants: 100
Treatment Group(s): 1
Primary Treatment: Observation group
Phase:
Study Start date:
June 01, 2024
Estimated Completion Date:
November 01, 2026

Connect with a study center

  • Ippokratio General Hospital

    Thessaloniki, 54642
    Greece

    Active - Recruiting

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