Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer

Last updated: September 29, 2025
Sponsor: ADVANCED MARKER DISCOVERY S.L.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carcinoma

Cancer/tumors

Colorectal Cancer

Treatment

N/A

Clinical Study ID

NCT06889883
AMD-CCR-2022-02
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical data of patients diagnosed with CRC or AA and healthy individuals.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients over the age of 18 who are able to understand the participant informationand sign the informed consent.

  • Patients who are going to undergo colonoscopy or surgical resection for tumor (CRC).

Exclusion

Exclusion Criteria:

  • Patients who had developed any type of cancer in the 5 years prior to theirparticipation in this study.

  • Patients who have received previous chemotherapy or radiotherapy.

  • Patients diagnosed with non-advanced adenomas, serrated polyps, Familial AdenomatousPolyposis or Lynch Syndrome.

  • Patients with inadequate bowel preparation for colonoscopy.

  • Patients who have undergone colonoscopy/polipectomy in the previous 5 years.

  • Patients with hemolyzed plasma.

Study Design

Total Participants: 510
Study Start date:
June 06, 2023
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Hospital Clinico Universitario Lozano Blesa

    Zaragoza 3104324, Aragon 3336899
    Spain

    Active - Recruiting

  • Hospital Universitario de Cruces

    Bilbao 3128026, Basque Country 3336903
    Spain

    Active - Recruiting

  • Policlinica Gipuzkoa Hospital

    Donostia / San Sebastian 3110044, Basque Country 3336903
    Spain

    Completed

  • Hospital Universitario Marques de Valdecilla

    Santander 3109718, Cantabria 3336898
    Spain

    Terminated

  • Hospital Universitario de Salamanca

    Salamanca 3111108, Castille and León 3336900
    Spain

    Active - Recruiting

  • Hospital Sant Rafael

    Barcelona 3128760, Catalonia 3336901
    Spain

    Completed

  • Hospital Universitario Vall d' Hebron

    Barcelona 3128760, Catalonia 3336901
    Spain

    Completed

  • Hospital Sant Rafael

    Barcelona, Cataluña
    Spain

    Completed

  • MD Anderson Cancer Centre

    Madrid 3117735, Madrid 3117732
    Spain

    Site Not Available

  • Hospital Centro Médico de Asturias

    Oviedo 3114711, Principality of Asturias 3114710
    Spain

    Active - Recruiting

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