The Management of Asymptomatic Carotid Stenosis

Last updated: March 15, 2025
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carotid Artery Disease

Treatment

N/A

Clinical Study ID

NCT06882954
2691
  • Ages > 18
  • All Genders

Study Summary

Carotid stenosis are asymptomatic if no hemispheric or retinal symptoms have appeared in the 6 months preceding the discovery of the stenosis. Asymptomatic carotid stenosis (ACS) accounts for about ¾ of all carotid lesions. The goal of treating carotid stenosis is to prevent a stroke. While carotid surgery is recommended in the elderly patients in cases of symptomatic carotid stenosis, that of ACS in patients over 75 years old, even when tight, remains subject to many controversies. Indeed, the debate, concerning the benefit to be expected from a surgical procedure or a possible angioplasty procedure, is not yet closed. The aim of our study, through a retrospective evaluation of the results of all consecutive carotid endarterectomy (CEA) and stenting in the participating center.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Asymptomatic carotid stenosis

  • Patient with degree of carotid stenosis greater than 80% measured by the maximumsystolic velocity at the site of the stenosis which must have been greater than 250cm/s

  • Ultrasound characteristics of a possibly unstable plaque

Exclusion

Exclusion Criteria:

  • Symptomatic carotid artery stenosis

Study Design

Total Participants: 500
Study Start date:
January 01, 2019
Estimated Completion Date:
December 31, 2027

Connect with a study center

  • Fondazione Policlinico Universitario A. Gemelli IRCCS

    Roma, RM 00167
    Italy

    Active - Recruiting

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