ISB With SSNB & ANB

Phase

N/A

Condition

N/A

Treatment

Preemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block

Clinical Study ID

NCT06878391

2024-12-010-003

Ages > 20
All Genders

Study Summary

This study is a prospective, randomized, double-blind trial comparing patients who underwent arthroscopic rotator cuff repair and received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with suprascapular nerve block and axillary nerve block (each with 10 ml of 0.75% ropivacaine) versus those who received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with placebo suprascapular and axillary nerve blocks (each with 10 ml of 0.9% saline).

The study will compare subjective pain scores (VAS score) and patient satisfaction preoperatively and at 1, 3, 6, 12, 18, 24, 36, and 48 hours postoperatively. Additionally, 5 ml of venous blood will be collected preoperatively and at 1, 6, 12, 24, and 48 hours postoperatively to analyze and compare serum levels of cortisol, IL-6, IL-8, IL-1β, substance P, serotonin, β-endorphin, and norepinephrine.

Eligibility Criteria

Inclusion

Inclusion Criteria:

a definite rotator cuff tear that needed repair seen on preoperative magneticresonancce imaging (MRI)
acceptance of arthroscopic surgery including rotator cuff repair
age same as or more than 20 years
acceptance of preemptive regional block and PCA, and blood testing

Exclusion

Exclusion Criteria:

did not undergo arthroscopic rotator cuff repair
stopped PCA before 48 hours postoperatively because of associated side effects
a history of previous ipsilateral shoulder operation or fracture
a concomitant neurologic disorder around the shoulder
a failure of blood sampling including hemolysis, etc.

Study Design