NENCA Study on Neurological Complications of Long COVID-19 in Children and Adolescents; Neurophysiological, Electroencephalographic and Neuroradiological Investigation

Inclusion Criteria:

• Age between 6 years and 16 years and 11 months

• Symptomatology compatible with long neurological COVID, specifically: persistence orappearance of new neurological signs/symptoms (e.g. fatigue, headache, sleepdisturbance, cognitive dysfunction, memory difficulties, emotional or mooddisorders, vertigo cognitive dysfunction, memory difficulties, emotional or mooddisorders, dizziness, dysautonomia, movement disorders movement disorders, ataxia,tremor, epilepsy, muscle weakness, myalgia, hyposmia, hypogeusia hearing loss ortinnitus and/or sensorimotor deficits such as hypoesthesia, dysesthesia) after threemonths after established SARS-CoV-2 infection, as well as persistence of thesesymptoms for at least two months, in the absence of a clear aetiology.

• Signature of the appropriate Informed Consent by caregiver(s) and patient(s)

Exclusion Criteria:

• Poor knowledge of the Italian language or other limitation of verbal communicationthat compromises the subject's ability to perform neuropsychological tests

• Need for sedation to perform brain MRI 7 Tesla

• Neurological or neuropsychiatric disorder diagnosed prior to COVID-19 diagnosis

• Caregiver's failure to sign consent