Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery

Last updated: March 17, 2025
Sponsor: Nanchong Central Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Colon Cancer

Colon Cancer; Rectal Cancer

Rectal Cancer

Treatment

Intraoperative area irrigation

Clinical Study ID

NCT06869096
2024135
  • Ages 18-85
  • All Genders

Study Summary

The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery. The primary outcomes included surgical site infection, postoperative complication rates, et al.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients aged 18-85 years,

  2. Patients with surgically resectable colorectal tumors confirmed by CT/MRI beforesurgery

  3. All patients had a performance status score of 0 or 1 in the Eastern TumorCooperative group

  4. American Society of Anesthesiology grade I-III

Exclusion

Exclusion Criteria:

  1. The tumor may have distant metastasis

  2. History of previous abdominal surgery

  3. The patient has a history of other malignant tumors diagnosed in the past 5 yearsand has received radiotherapy and chemotherapy in the past

  4. There are obvious contraindications to surgery (obvious abnormal liver and kidneyfunction, pregnancy)

  5. Participated in other clinical trials within the past 6 months

Study Design

Total Participants: 532
Treatment Group(s): 1
Primary Treatment: Intraoperative area irrigation
Phase:
Study Start date:
July 02, 2024
Estimated Completion Date:
March 01, 2026

Connect with a study center

  • Nanchong Central Hospital

    Nanchong, Sichuan 637000
    China

    Active - Recruiting

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