Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.

Phase

N/A

Condition

N/A

Treatment

Collecting questionnaires and biological samples

Clinical Study ID

NCT06862843

DIETA-MICIREUMA

All Genders
Accepts Healthy Volunteers

Study Summary

The proposed study is part of a PNRR 2022 project (call "Non-Communicable Chronic Diseases (NCDs) with high impact on healthcare and social assistance systems," currently awaiting funding response) and represents the continuation of an observational clinical study named TRANSMIC, approved by the pediatric ethics committee of the Tuscany region. TRANSMIC was an integral part of a European research project within the joint programming initiative (JPI), under the HDHL-INTIMIC theme: "A Healthy Diet for a Healthy Life," aimed at understanding the cause-effect relationships between diet, gut microbiome, and human health.

Understanding the role of diet in inflammatory bowel diseases (IBD) and exploring its role in autoimmune inflammatory conditions with joint manifestations, such as JIA, provides additional insights into the development, progression, and management of these conditions, opening new horizons for the use of dietary treatments in preventing these inflammatory conditions.

Eligibility Criteria

Inclusion

Inclusion Criteria:

For families with at least one child/adult affected by IBD/JIA:

Father and mother with children aged between 0-18 years, in good health.
At least one adult or one child affected by IBD, or a child affected by JIA,regardless of ongoing therapy and without distinction of disease severity oractivity.

For healthy families:

Father and mother with children aged between 0-18 years, in good health and notaffected by chronic inflammatory bowel diseases or chronic autoimmune inflammatorydiseases in general.

Exclusion

Exclusion Criteria:

For subjects affected by IBD:

Monogenic disease
Children with an ileostomy or who have undergone a colectomy

For subjects affected by JIA:

No exclusion criteria

For healthy subjects:

Any chronic inflammatory bowel disease, autoimmune disease, or ongoing infectiousdiseases.

Study Design

Collecting questionnaires and biological samples

February 07, 2024

November 15, 2025

Connect with a study center

AOU Meyer IRCCS
Florence,
Italy
Active - Recruiting
Università di Foggia
Foggia,
Italy
Active - Recruiting
Ospedale Villa Sofia Cervello, Università di Palermo
Palermo,
Italy
Active - Recruiting
Università La Sapienza di Roma
Roma, 00185
Italy
Active - Recruiting

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