Improving Maternal Cardiovascular Outcomes Through the Implementation of a Hypertensive Disorders of Pregnancy Bundle in Nigeria

Last updated: February 27, 2025
Sponsor: Washington University School of Medicine
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pregnancy Complications

Williams Syndrome

Circulation Disorders

Treatment

Hypertension Disorders of Pregnancy (HDP) Implementation Bundle

Clinical Study ID

NCT06859359
202311185
K23HL173684
  • Female

Study Summary

The goal of this interventional study is to learn from patients and healthcare providers at 4 health institutions (study sites) in Abuja and Kano in Nigeria what ways to best develop the content of a Hypertensive Disorders of Pregnancy ( HDP) Management package for pregnant women, and evaluate the effectiveness of implementing this package in improving cardiovascular health of pregnant women. The main question it aims to answer is:

Will a contextualized home BP monitoring program lead to better BP control among patients with HDP in Nigeria?

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Postpartum adults (>18 years)

  • postpartum emancipated minors (in accordance with the Nigerian guidelines for youngpersons' participation in research and reproductive health services)

  • with diagnosis of HDP prior to delivery delivered at one of the participating sitesable to provide informed consent.

Exclusion

Exclusion Criteria:

  • unable to provide consent.

Study Design

Total Participants: 1200
Treatment Group(s): 1
Primary Treatment: Hypertension Disorders of Pregnancy (HDP) Implementation Bundle
Phase:
Study Start date:
August 08, 2024
Estimated Completion Date:
June 30, 2029

Study Description

This study aims to contextualize, implement, and evaluate the feasibility, fidelity, and acceptability and effectiveness of: 1) postpartum remote blood pressure monitoring, 2) patient education, 3) development of a standardized postpartum follow-up protocol, and 4) provision of free and/or subsidized antihypertensive medications for patients with HDP in University of Abuja, Murtala Muhammad Specialist Hospital, National Hospital, Abuja and Aminu Kano Teaching Hospital all in Nigeria. These components collectively make up a contextualized postpartum BP monitoring program called the HDP Implementation Bundle. The long-term objective is to implement a contextualized and acceptable evidence-based postpartum home BP monitoring program with supporting services and components, at 4 tertiary care institutions in Nigeria, to improve postpartum BP control in patients with HDP using a multilevel approach.

Connect with a study center

  • National Hospital, Abuja

    Abuja,
    Nigeria

    Active - Recruiting

  • University of Abuja Teaching Hospital

    Abuja,
    Nigeria

    Active - Recruiting

  • Aminu Kano Teaching Hospital

    Kano,
    Nigeria

    Active - Recruiting

  • Murtala Muhammad Specialist Hospital

    Kano,
    Nigeria

    Active - Recruiting

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