Perioperative Analgesia with Erector Spinae Plane Block in Liver Transplant Recipients

Last updated: February 26, 2025
Sponsor: Bogomolets National Medical University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Erector Spinae Plane Block using 0.2% ropivacaine

Clinical Study ID

NCT06857331
190
  • All Genders

Study Summary

The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant. The main question it aims to answer are Is ESP block safe and has a minimum side effects, like hematoma? Is it effective for perioperative analgesia? Researchers will compare the results to a group of patients who underwent liver transplants without any regional anaesthesia techniques.

Participants will receive bilateral thoracic ESP block on the day of the transplantation with a subsequent bilateral catheterization.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • impaired liver function - cirrhosis or chronic liver disease with the development ofhypocoagulation (APTT > 35 sec, INR > 1.5), thrombocytopenia, patients requiringmajor abdominal surgery, age > 18 years, written consent to participate in the studywas obtained

Exclusion

Exclusion Criteria:

  • Platelet count <50x109, failed ESP catheterization unilateral or bilateral, failedepidural anesthesia attempt, history of allergy or hypersensitivity to localanesthetics, hepatopulmonary syndrome, patients on mechanical ventilation beforesurgery, patients on CRRT before surgery, refusal to participate in the study

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Erector Spinae Plane Block using 0.2% ropivacaine
Phase:
Study Start date:
May 05, 2024
Estimated Completion Date:
December 10, 2025

Connect with a study center

  • Universal Hospital Oberig

    Kyiv,
    Ukraine

    Active - Recruiting

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