Pericapsular Nerve Group With Lateral Femoral Cutaneous Nerve Block vs Suprainguinal Fascia Iliaca Block for Analgesia in Total Hip Arthroplasty: A Prospective Comparative Study

Last updated: August 25, 2025
Sponsor: Hacettepe University
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT06844162
KA-22088
  • Ages 18-90
  • All Genders

Study Summary

Prospective observational cohort comparing analgesic efficacy of suprainguinal fascia iliaca block (SFIB) vs pericapsular nerve group block combined with lateral femoral cutaneous nerve block (PENG+LFCN) in primary total hip arthroplasty under general anesthesia (n=48). Outcomes include VAS pain at rest and with movement at 3, 12, 24, 48 h; morphine use (0-3, 3-12, 12-24, 24-48 h; total 0-48 h); quadriceps strength at 6 and 24 h; physiotherapy participation at 24 and 48 h; and adverse events within 48 h.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients who are scheduled to undergo primary total hip arthroplasty with adiagnosis of coxarthosis

Exclusion

Exclusion Criteria:

  • Patients who have a history of neuropathy, patients with renal and hepaticinsufficiency, patients with known coagulopathy, patients with a history of allergyto local anesthetics, patients with a history of inguinal surgery on the same sideand patients with impaired mental status

Study Design

Total Participants: 48
Study Start date:
February 01, 2024
Estimated Completion Date:
April 15, 2024

Study Description

Adults undergoing primary posterolateral THA under general anesthesia were included if they received either SFIB or PENG+LFCN. Pain (VAS at rest and with 45° passive flexion) was recorded at 3, 12, 24, and 48 h. Morphine via PCA was recorded for 0-3, 3-12, 12-24, and 24-48 h, with a 0-48 h total. Quadriceps strength (0-2 scale) was assessed at 6 and 24 h; physiotherapy participation at 24 and 48 h; opioid- or block-related adverse events through 48 h.

Connect with a study center

  • Hacettepe University Hospitals

    Ankara, 06230
    Turkey

    Site Not Available

  • Hacettepe University Hospitals

    Ankara 323786, 06230
    Turkey (Türkiye)

    Site Not Available

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