Immediate Implant Placement Using Xenograft Mixed with Vitamin D Versus Hyaluronic Acid.

Last updated: February 19, 2025
Sponsor: Cairo University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Hyaluronic Acid (HA)

Vitamin D

Clinical Study ID

NCT06842368
A.M.A.E
  • Ages 18-60
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Immediate implant placement using xenograft as space filling material mixed with vitamin D versus hyaluronic acid in posterior mandible region This study aims to evaluate implant stability and density after placement of immediate implant and Xenograft mixed with Hyaluronic acid or Vitamin D at posterior mandible region

Eligibility Criteria

Inclusion

Inclusion Criteria:

Age: 18-60.

  • Systemically healthy patients indicated for single or multiple immediate implants inposterior teeth region.

  • Absence of any peri-apical pathosis.

  • Patients with intact buccal plate of bone.

  • Patients with adequate bone volume for the dental implant procedure.

  • Patient with good oral hygrine

Exclusion

Exclusion Criteria:

  • Heavy Smokers.

  • Systemic disease that may affect the final outcome of the surgical procedure.

  • No or poor patient's compliance.

  • Patients with psychological problems.

  • Pathology at the site of intervention.

  • Patient with vit d deficiency

Study Design

Total Participants: 24
Treatment Group(s): 2
Primary Treatment: Hyaluronic Acid (HA)
Phase:
Study Start date:
February 02, 2025
Estimated Completion Date:
October 30, 2025

Study Description

Dental implants in fresh extraction sockets and healed sites have a erratic morphology, creating a wide space defect between the implant and buccal alveolar bone. This defect is critical for implant success, known as a jumping gap. Proper management of this space is essential for esthetic and functional success. Studies show adequate bone fill can be achieved in jumping gaps, but wider gaps increase implant body exposure risk.

The application of biological mediators embedded in the biomaterial can induce specific cell and tissue response, which can improve bone quality and quantity. Dental research has focused on improving bone substitutes by morphologic or bio- chemical modification.

Connect with a study center

  • Faculty of dentistry ,Cairo university

    Cairo,
    Egypt

    Active - Recruiting

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