Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy

Last updated: February 20, 2025
Sponsor: Ain Shams University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Rectus sheath block

Intrathecal morphine

Clinical Study ID

NCT06837506
FMASU R03/2024/2025
  • Ages 18-65
  • Female

Study Summary

This study aims to compare the effectiveness and safety of ultrasound-guided rectus sheath block versus intrathecal morphine for postoperative analgesia in patients undergoing open total abdominal hysterectomy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age: 18 - 65 years old.

  • American Society of Anesthesiologists (ASA) physical status (I -II).

  • Patients undergoing open total abdominal hysterectomy.

Exclusion

Exclusion Criteria:

  • Hepatic, renal, or cardiac disease.

  • Any known allergy to local anesthetic.

  • Physical or mental conditions which may vague measuring postoperative pain followingsurgery.

  • History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs)or central nervous system (CNS) depressants as antiepileptic, and bleedingdisorders.

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: Rectus sheath block
Phase:
Study Start date:
February 20, 2025
Estimated Completion Date:
August 01, 2025

Study Description

Effective postoperative analgesia is crucial for enhancing recovery and patient satisfaction following major surgical procedures, such as total abdominal hysterectomy (TAH).

Rectus sheath block (RSB), an ultrasound-guided regional anesthesia technique, involves the injection of local anesthetic into the rectus sheath, providing analgesia to the anterior abdominal wall. RSB is used to block the sensory nerves of the anterior abdominal wall and thereby contributing to pain relief after lower abdominal surgeries.

Intrathecal morphine (ITM) provides a highly effective method of analgesia by delivering the medication directly into the cerebrospinal fluid (CSF).

Connect with a study center

  • Ain Shams University

    Cairo, 11591
    Egypt

    Active - Recruiting

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