Diagnosis and Outcomes of Placental Accretism

Last updated: February 11, 2025
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT06833606
PLC_AC
  • Ages 18-44
  • Female

Study Summary

The goal of this observational study is to evaluate the diagnostic ability of the main criteria currently adopted for the diagnosis of placenta accreta and to define the maternal outcomes in terms of complications of the different management strategies currently adoptable when placental accretism is suspected.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age between 18 years and 44 years

  • Pregnant women with suspected placental accretism

  • Acquisition of informed consent form

Exclusion

Exclusion Criteria:

None

Study Design

Total Participants: 70
Study Start date:
July 17, 2023
Estimated Completion Date:
December 31, 2026

Study Description

Currently, the management of cases of placental accretism/percretism is not standardized. This study could help in assessing maternal and fetal outcomes related to the different therapeutic strategies applied in the clinical cases under study so that their management can be standardized in the near future.

This is a retrospective and prospective, national multicenter study. Patients will be treated according to clinical practice.

The main instrumental findings of cases of suspected accretism will be collected and analyzed, and the progression of pregnancy and postpartum (by means of laboratory and instrumental tests) will be evaluated in order to define the outcomes of conservative management (cesarean section with placenta in situ) versus more radical management (cesarean section and concomitant hysterectomy).

In particular, clinical trends (by means of assessment of vital parameters, laboratory tests, ultrasound images or instrumental examinations) in pregnancy, in the immediate postoperative period and during subsequent outpatient follow-up visits will be analyzed.

In general, in the absence of complications, visits will be performed twice a week during pre-partum. Postpartum follow-up is not standardized, as it will depend strictly on the procedure performed and the occurrence or absence of complications. There are no questionnaires and/or rating scales.

Connect with a study center

  • Ospedale "M. Bufalini"

    Cesena, Forlì-Cesena 47521
    Italy

    Active - Recruiting

  • Ospedale "Morgagni-Pierantoni"

    Forlì, Forlì-Cesena 47121
    Italy

    Active - Recruiting

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    Bologna, 40138
    Italy

    Active - Recruiting

  • AOU Policlinico di Modena

    Modena, 41100
    Italy

    Active - Recruiting

  • Azienda Ospedaliero - Universitaria di Parma

    Parma, 43126
    Italy

    Active - Recruiting

  • Arcispedale Santa Maria Nuova

    Reggio Emilia, 42123
    Italy

    Active - Recruiting

  • Ospedale "Infermi" di Rimini

    Rimini, 47900
    Italy

    Active - Recruiting

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