Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome

Last updated: March 18, 2025
Sponsor: Centre Hospitalier Universitaire de Nice
Overall Status: Active - Recruiting

Phase

N/A

Condition

Dry Eyes

Sjogren's Syndrome

Dry Eye Disease

Treatment

injections of Platelet-Rich Plasma in lacrimal gland

Clinical Study ID

NCT06831253
24-AOIP-02
IDRCB
  • Ages > 18
  • All Genders

Study Summary

The investigatror wants to show the efficacy of Platelet-Rich Plasma injection in lacrimal gland to restore the lacrimal secretion in patients presenting aqueous deficiency reponsible for severe dry eye syndrome.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Platelet counts, and clotting factors in the standarts

  • Presenting with severe dry keratoconjunctivitis diagnosed by an ophthalmologist

Exclusion

Exclusion Criteria:

  • Patients with significant fibrosis of the conjunctival portion of the lacrimal gland

  • Patients with complete stenosis of both lacrimal meatus in the treated eye

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: injections of Platelet-Rich Plasma in lacrimal gland
Phase:
Study Start date:
March 17, 2025
Estimated Completion Date:
July 01, 2026

Study Description

injections in lacrimal gland four times during the study for each patient

Connect with a study center

  • CHU de Nice

    Nice, Site Principal Investigator 06000
    France

    Active - Recruiting

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