Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile

Last updated: January 15, 2026
Sponsor: Alexandria University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

cut umbilical milking

intact umbilical milking

Delayed cord clamping

Clinical Study ID

NCT06812507
0107951
  • Ages 1-2
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in premature neonates over the first days of life

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  1. Premature neonates ≤ 32 weeks gestational age regardless birth weight

  2. patients should be admitted to neonatal intensive care unit in the first day oflife of life

Exclusion

Exclusion criteria:

  • Exclusion Criteria:

Patient with any of the following will be excluded:

  1. Major congenital anomalies (complex cyanotic heart disease, major central nervoussystem anomalies).

  2. Evidence of head trauma causing major intracranial hemorrhage.

  3. placental abnormalities like : abruptions, placenta previa or retroplacentalhematoma.

  4. Cord accident, or avulsion at the time of delivery.

  5. Refusal to perform the intervention by the obstetrician

Study Design

Total Participants: 160
Treatment Group(s): 3
Primary Treatment: cut umbilical milking
Phase:
Study Start date:
March 10, 2025
Estimated Completion Date:
April 28, 2026

Connect with a study center

  • Marwa Mohamed Farag

    Alexandria, 0325
    Egypt

    Site Not Available

  • Marwa Mohamed Farag

    Alexandria 361058, 0325
    Egypt

    Active - Recruiting

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