The Effects of Brown Rice Compared to White Rice on Postprandial Changes in IL-6 and MDA Levels in Sedentary Workers

Last updated: January 21, 2025
Sponsor: Indonesia University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Inflammation

Treatment

rice wheat (placebo)

RICE

Clinical Study ID

NCT06780618
24-10-1628
  • Ages 21-59
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The goal of this clinical trial is to learn if brown rice and white rice affect oxidative stress and inflammation in office workers who don't exercise much. The main question it aims to answer is:

Does eating brown rice change MDA and IL-6 levels differently than eating white rice in people who don't exercise much?

Participants will:

Be interviewed to collect personal data, medical history, lifestyle habits, and dietary patterns.

Be measured to calculate Body Mass Index (BMI). Be interviewed to complete a questionnaire to assess their physical activity level in the past week.

Be interviewed to record all food and beverages consumed in the past 24 hours. Blood samples will be drawn twice, before and after consuming the research meal.

Be provided with a research meal consisting of rice (either brown or white), scrambled eggs, and tofu stew that must be finished within 15 to 20 minutes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • healthy administrative employees,

  • age 21-59 years,

  • normal body mass index (18.5-22.9 kg/m2),

  • low physical activity (≤600 METs minutes/week),

  • assign for informed consent

Exclusion

Exclusion Criteria:

  • being pregnant/breastfed/menopause,

  • consumption of herbal medicines and/or supplements within 24 hours before datacollection,

  • having history of DM, CVD, cancer, and autoimmune disease,

  • being vegan,

  • smoking/alcohol drinking,

  • allergic to research food's ingredients

Study Design

Total Participants: 30
Treatment Group(s): 2
Primary Treatment: rice wheat (placebo)
Phase:
Study Start date:
January 06, 2025
Estimated Completion Date:
April 30, 2025

Connect with a study center

  • Faculty of Medicine University of Indonesia

    Jakarta,
    Indonesia

    Active - Recruiting

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