Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction

Inclusion Criteria:

1. Patient male or female with age ≥18 years old

2. Patient with diagnosis of shoulder soft tissue inflammation due to SAIS/RCT (asconfirmed by physical examination and/or imaging) to be treated by LightForce®Therapy Lasers according to its indications.

3. Patient suffering from shoulder soft tissue inflammation due to SAIS/RCT pain formore than 3 months prior to enrollment

4. Pain (either persistent or during activities) score reported by the subject atbaseline ≥ 40 mm measured on VAS

5. Patient able to provide written informed consent

Exclusion Criteria:

1. Patient with musculoskeletal pathological conditions not to be treatedwith/contraindication to the use of LightForce® Therapy Lasers according to itsintended use and indications

2. Patients who are taking drugs that have heat or light sensitive contraindications,such as but not limited to certain types of steroids

3. Patients who are administered with corticosteroids, should discontinue the treatmentat least 2 weeks prior to study treatment start

4. Pregnant females or females of childbearing potentially planning to become pregnantduring the study participation

5. Patients who had systemic inflammatory conditions (i.e.rheumatoid arthritis,polymyalgia rheumatica)

6. Patients who underwent intra-articular injection (Ialuronic acid, platelet richplasma or corticosteroids) in the shoulder in the last 3 months

7. Patients who have a disease that would limit their participation in exercises (i.e.severe chronic obstructive pulmonary disease, severe heart failure, cerebrovascularevent history)

8. Patients with a prior history of surgical intervention and implantation of a metalimplant into the affected shoulder

9. Patients with a diagnosis of active cancer

10. Patients with tattoos covering more than 30% of the area to be treated withLightForce® Therapy Lasers

11. Patients who are mentally or physically incapacitated

12. Patient participating in other clinical study or has completed a clinical study lessthan 30 days prior to enrollment

13. Patient affected by shoulder soft tissue acute inflammation due to recent sportinjury or trauma

14. Patients with other musculoskeletal problems of the shoulder joint such ascalcifying tendinitis, full thickness rotator-cuff tear, adhesive capsulitis,fibromyalgia, recent surgery or fracture of the shoulder joint, and/or undergoing tospecific physiotherapy for these ("recent" is defined as within 30 days prior toenrollment).

15. Patients with other clinically significant co-morbidities that make the patientunsuitable for study participation, at the discretion of the investigator