Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

Last updated: December 26, 2024
Sponsor: Sohag University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Ketamine-Propofol

Dexmedetomidine-Propofol

Clinical Study ID

NCT06756594
Soh-Med-24-11-02MS
  • Ages 18-60
  • All Genders

Study Summary

This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • American Society of Anesthesiologists physical status I to II.

  • Age between 18 and 60 years.

  • Both sexes.

Exclusion

Exclusion Criteria:

  • Having severe heart, lung, liver disease, kidney failure, or bleeding disorder.

  • Patients having fever, hypothermia or infection, electrolyte disorders, such ashypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Ketamine-Propofol
Phase:
Study Start date:
November 12, 2024
Estimated Completion Date:
June 11, 2025

Connect with a study center

  • Sohag University Hospital

    Sohag,
    Egypt

    Active - Recruiting

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