Interprofessional Pharmacogenomics (IPGx) Registry and Repository

Inclusion Criteria:

• The study will invite patients who are eligible for PGX workup/PGX care toparticipate, provided they meet the following criteria: Use of five or moremedications, including over the counter drugs, supplements, natural products,cannabis products, or other recreational drugs, or

• Individuals taking blood pressure or depression medications, even if less than fivemedications.

• Ability to understand and give consent.

• Able to consent to donate blood and/or urine samples and buccal swabs.

• Able to answer detailed questionnaires, including quarterly questionnaires aboutADRs, cognitive testing such as serial mini-mental status exams, and or quality oflife questions.

• Able to understand that their health record and changes in health status will befollowed for a five-year period and shared in deidentified form with the researchcommunity.

• All genders.

• Any age over 18 years.

Exclusion Criteria:

• Individuals admitted to hospice.

• Declines to participate or interact with staff/share their medical status.

• A diagnosis of Alzheimer's disease or related dementias in a medical record as thisindicates a progressive, debilitating condition that impairs memory, thoughtprocesses, and functioning.,

• Individuals who are unable or unwilling to provide consent.

• Unable to verbally communicate and comprehend English language