Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Last updated: December 2, 2024
Sponsor: Michael J. Fox Foundation for Parkinson's Research
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT06719583
BLAAC PD
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities.

BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.

Eligibility Criteria

Inclusion

Inclusion Criteria for Control Participants:

  • Ability to provide informed consent

  • Age 18 years or older

  • Self-identify as Black or African American

Exclusion Criteria for Control Participants:

  • Diagnosis of Parkinson's Disease and/or neurological condition

  • Familial history of PD and/or neurodegenerative or psychiatric conditions

  • Unknown family history of PD and/or neurodegenerative or psychiatric conditions

  • Any conditions that, in the investigator's opinion, preclude the individual's ability to carry out study activities

  • If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection

Inclusion Criteria for Participants with a Diagnosis of PD:

  • Ability to provide informed consent

  • Age 18 years or older

  • Self-identify as Black or African American

  • Meet the Movement Disorder Society's clinical diagnostic criteria for Parkinson's disease

Exclusion Criteria for Participants with a Diagnosis of PD:

  • If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection

Study Design

Total Participants: 2000
Study Start date:
November 16, 2020
Estimated Completion Date:
December 31, 2026

Study Description

Research studies have found connections between genes and Parkinson's disease (PD). But those results have mostly come from studies with non-Black or African American volunteers. BLAAC PD aims to learn more about gene changes that may cause Parkinson's in Black and African American people. Study volunteers at sites across the United States will attend one visit and will give either a blood or saliva sample, complete a smell test, and may be asked to complete a physical exam. This new data could lead to future Parkinson's tests and treatments for Black and African American people and it may help better understand disease in other groups, too.

This pioneering initiative will fill a gap of knowledge about PD in Black and African American people.

Connect with a study center

  • University of Alabama at Birmingham

    Birmingham, Alabama 35233
    United States

    Active - Recruiting

  • University of Florida

    Gainesville, Florida 32608
    United States

    Active - Recruiting

  • Rush University

    Chicago, Illinois 60612
    United States

    Active - Recruiting

  • University of Chicago

    Chicago, Illinois 60637
    United States

    Active - Recruiting

  • Ochsner Clinic Foundation

    New Orleans, Louisiana 70121
    United States

    Active - Recruiting

  • Louisiana State University Health Sciences Center Shreveport

    Shreveport, Louisiana 71103
    United States

    Active - Recruiting

  • University of Maryland

    Baltimore, Maryland 21201
    United States

    Active - Recruiting

  • Kaiser Permanente Midatlantic States

    Rockville, Maryland 20852
    United States

    Site Not Available

  • Washington University in St. Louis

    Saint Louis, Missouri 63119
    United States

    Active - Recruiting

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio 44106
    United States

    Active - Recruiting

  • Medical University of South Carolina

    Charleston, South Carolina 29425
    United States

    Active - Recruiting

  • University of Texas Health Science Center, Houston

    Houston, Texas 77030
    United States

    Active - Recruiting

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