First-Line Intervention for PTSD - Intensive Treatment

Last updated: February 27, 2025
Sponsor: ARQ National Psychotrauma Centre
Overall Status: Active - Recruiting

Phase

N/A

Condition

Post-traumatic Stress Disorders

Treatment

Intensive Treatment

Treatment as usual

Clinical Study ID

NCT06700590
NL86057.018.24
10390092110006
  • Ages > 18
  • All Genders

Study Summary

The goal of this clinical trial is to learn if an intensive program can treat post-traumatic stress disorder (PTSD) in adults getting treatment for the first time, and whether it has lower societal costs. The main questions it aims to answer are:

  • Does an intensive program reduce PTSD symptoms?

  • How expensive is it on a societal level? Researchers will compare the intensive program to the standard weekly treatment to see if the intensive program works to treat PTSD.

Participants will:

  • Get 5 days of intensive treatment in two weeks (with two preparatory and closing sessions), or weekly sessions

  • Get questionnaires and interviews 5 times in 9 months

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18 years or older

  • PTSD diagnosis according to DSM-5 (CAPS-5);

  • PTSD diagnosis stemming from 2 or more potentially traumatic events (PTEs)

  • seeking first-time treatment for PTSD (or less than 8 sessions);

  • employed (working or on sick leave for less than two years)

Exclusion

Exclusion Criteria:

  • Current psychotic disorder, severe alcohol or substance use disorder, high suicidalintent (MINI-S for DSM-5) and a concrete suicide plan, or severe aggressive behaviorthat poses danger for others

  • insufficient command of the Dutch language to be able to complete the assessments.This will be determined through clinical judgment at intake.

Study Design

Total Participants: 186
Treatment Group(s): 2
Primary Treatment: Intensive Treatment
Phase:
Study Start date:
November 21, 2024
Estimated Completion Date:
July 01, 2028

Connect with a study center

  • ARQ IVP

    Diemen, Noord-Holland 1112 XE
    Netherlands

    Active - Recruiting

  • Psychotraumacentrum Haarlem

    Haarlem, Noord-Holland 2011 VE
    Netherlands

    Active - Recruiting

  • ARQ Centrum'45

    Oegstgeest, Zuid-Holland 2342 AX
    Netherlands

    Active - Recruiting

  • Psy-Zo!

    Groningen, 9747 AN
    Netherlands

    Active - Recruiting

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