Phase
Condition
Stomach Discomfort
Bowel Dysfunction
Lactose Intolerance
Treatment
Mirtazapine
Placebo
Clinical Study ID
Ages 18-70 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Participants must meet all of the inclusion criteria to participate in this study:
Adults (ages 18-70)
Score of >175 on the IBS-SSS questionnaire
Must meet Rome IV criteria for IBS-D
If subject is of reproductive capability a negative urine pregnancy test mustbe available prior to entering the study
Ability to understand study procedures and to comply with them for the entirelength of the study
Exclusion
Exclusion Criteria:
All candidates meeting any of the below exclusion criteria at baseline will beexcluded from study participation:
Score of < 175 on the IBS-SSS
Prior diagnoses of: known celiac disease, small intestinal bacterialovergrowth, inflammatory bowel disease, or microscopic colitis
Ongoing significant anxiety or depression
A history of a known side effect to mirtazapine
Prior treatment with a low FODMAP diet or mirtazapine without clinical benefit
Active alcohol or drug abuse
Inability to read or understand the consent form
Any other medical or psychological reason that would prevent activeparticipation in a research study
Pregnant females
Study Design
Study Description
Connect with a study center
Mayo Clinic
Jacksonville, Florida 32224
United StatesActive - Recruiting
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.