Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection

Last updated: March 17, 2025
Sponsor: Khyber Medical University Peshawar
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pentalogy Of Cantrell

Hernia

Treatment

Heavy Weight Mesh

Light Weight Mesh

Clinical Study ID

NCT06644612
KMU/DIR/CTU/2024/008
  • Ages > 15
  • All Genders

Study Summary

This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh. The study aims to determine which mesh type results in fewer SSIs, thereby guiding future surgical approaches to abdominal hernia repair.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients aged 15 and above.

  • Patients undergoing primary abdominal hernia repair using light or heavy mesh.

Exclusion

Exclusion Criteria:

  • Patients with incisional hernias.

  • Patients with diabetes mellitus, chronic cough, steroid use, cancer, orimmune-compromised status.

Study Design

Total Participants: 106
Treatment Group(s): 2
Primary Treatment: Heavy Weight Mesh
Phase:
Study Start date:
August 01, 2024
Estimated Completion Date:
April 15, 2025

Study Description

Hernias, a protrusion of abdominal contents through the abdominal wall, are often treated surgically using synthetic polypropylene mesh. Two varieties of polypropylene mesh exist: light and heavy weighted. The lighter mesh is softer, less allergenic, and potentially leads to fewer post-surgical complications, including SSIs. In contrast, heavier mesh, which has been traditionally used, consists of thicker threads with narrower gaps and has a higher chance of eliciting an immune response. This trial aims to assess the effectiveness of light mesh over heavy mesh in reducing SSIs in abdominal hernia repairs, thereby providing data to support best practices in surgical care.

Connect with a study center

  • Lady Reading Hospital, Pakistan

    Peshawar, Khyber Pakhtunkhwa 25000
    Pakistan

    Active - Recruiting

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