Enhancing Palliative Care in ICU

Last updated: January 9, 2025
Sponsor: Charite University, Berlin, Germany
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cancer

Cancer Treatment

Treatment

Complex intervention

Routine treatment

Clinical Study ID

NCT06605079
EPIC
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of this study is to reduce the suffering in intensive care through palliative care consultations.

Eligibility Criteria

Inclusion

Patients:

Inclusion Criteria:

  • Patients in ICU who can give consent and those who can not (via their authorizedrepresentative or legal guardian, also possible with delayed consent)

  • From 18 years

  • The leading cause of critical illness is not cancer

  • New admission on the participating ICU > 72h

  • Assessment of the need for palliative care by the in-charge physi-cian of the ICU,because (1) there is a significant disagreement about ICU treatment or (2) becausethe physician considers ther-apy limitations for the patient or (3) the physicianconsiders a benefit from specialized PC consultation for ICU physician, nurse, orpatient or family.

Exclusion

Exclusion Criteria:

  • Patient is moribund and is expected to die within the next 24h

Study cohort relatives:

Inclusion criteria:

  • At least one relative(s) of a patient. This may or may not be the legalrepresentative, depending on national legislation.

Exclusion criteria:

  • Refusal by the relative

  • Refusal of the patient to participate in the intervention study

  • <18 years of age

Cohort of employees:

Inclusion criteria

  • Employed on the ITS as a doctor/nurse

  • Employed in the clinical center as a member of the palliative care consultationservice

Exclusion criterion Refusal to participate

Study Design

Total Participants: 2040
Treatment Group(s): 2
Primary Treatment: Complex intervention
Phase:
Study Start date:
October 10, 2024
Estimated Completion Date:
August 31, 2027

Study Description

This project investigates the effectiveness and cost-effectiveness of palliative care consultations in the Intensive care unit. Charité will implement the Working Package 2 "Europe-wide harmonized and recommended palliative care practice for ICU" of the approved HORIZON funding application EPIC, to which this ethics application refers.

An accompanying anonymous employee survey (doctors/nurses) is conducted once in the intervention phase and once in the control phase in all study centers (see secondary endpoints 57-68 and 71).

Connect with a study center

  • Deoartment of Palliative Medicine, GENERAL UNIVERSITY HOSPITAL IN PRAGUE VSEOBECNA FAKULTNI NEMOCNICE V PRAZE

    Praha, Prague
    Czechia

    Site Not Available

  • ICU General University hospital

    Prague,
    Czechia

    Active - Recruiting

  • CARITAS Klinik Maria Heimsuchung

    Berlin,
    Germany

    Active - Recruiting

  • Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), Charité- University Berlin

    Berlin, 13353
    Germany

    Active - Recruiting

  • Department of Cardiology, Angiology and Intensive Care Medicine | CVK, Charité - University Berlin

    Berlin,
    Germany

    Active - Recruiting

  • Evangelisches Krankenhaus Hubertus

    Berlin,
    Germany

    Active - Recruiting

  • Unfallkrankenhaus Berlin

    Berlin,
    Germany

    Active - Recruiting

  • Department of Anesthesiology and Intensive Care Medicine (CCM/CVK),Charité - University Medicine Berlin

    Berlin-Mitte,
    Germany

    Active - Recruiting

  • Medical and Neurological Intensive Care Unit, University Hospital of Düsseldorf

    Düsseldorf,
    Germany

    Active - Recruiting

  • Neurosurgical and Traumatological ICU ZI13, University Hospital of Düsseldorf

    Düsseldorf,
    Germany

    Active - Recruiting

  • Surgical Intensive Care Unit CIA1/CIB1, University Hospital of Düsseldorf

    Düsseldorf,
    Germany

    Active - Recruiting

  • Universitätsklinikum Halle (Saale): Klinik für Innere Medizin III

    Halle,
    Germany

    Active - Recruiting

  • Johanna-Etienne Hospital Neuss, Interdisciplinary ICU

    Neuss,
    Germany

    Active - Recruiting

  • Ev. Krankenhaus Paul-Gerhardt-Stift Wittenberg:Angiologie und Kardiologie

    Wittenberg,
    Germany

    Active - Recruiting

  • Department of Intensive Care Medicine, University Hospital of Heraklion

    Heraklion, Crete
    Greece

    Active - Recruiting

  • Department of Intensive Care Medicine, University Hospital of Patras

    Patras, Rio
    Greece

    Active - Recruiting

  • Department of Intensive Care Medicine, University Hospital of Alexandroupolis

    Alexandroupolis,
    Greece

    Active - Recruiting

  • Cardiothoracic Intensive Care Unit of the Onassis Cardiac Surgery Center

    Athens,
    Greece

    Active - Recruiting

  • Department of Intensive Care Medicine, Alexandra General Hospital

    Athens,
    Greece

    Active - Recruiting

  • Department of Intensive Care Medicine, Evaggelismos General Hospital

    Athens,
    Greece

    Active - Recruiting

  • First Department of Intensive Care Medicine Evaggelismos hospital, ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

    Athens,
    Greece

    Site Not Available

  • Department of Intensive Care Medicine, University Hospital of Ioannina

    Ioánnina,
    Greece

    Active - Recruiting

  • University Hospital of Larissa, Critical Care Department

    Larissa,
    Greece

    Active - Recruiting

  • General Intensive Care Unit, Hadassah Medical Organisation

    Jerusalem,
    Israel

    Active - Recruiting

  • The Coronary Care Intensive Care Unit, Hadassah Hospital, Ein Kerem

    Jerusalem,
    Israel

    Active - Recruiting

  • The Neurosurgical Intensive Care Unit, Hadassah Hospital, Ein Kerem

    Jerusalem,
    Israel

    Active - Recruiting

  • S.C. Anestesia e Rianimazione 1 - Terapia Intensiva Cardiochirurgica, Azienda Ospedaliera Universitaria S. Maria della Misericordia

    Perugia,
    Italy

    Active - Recruiting

  • S.C. Anestesia e Rianimazione 2 - Terapia Intensiva, Azienda Ospedaliera Universitaria S. Maria della Misericordia

    Perugia,
    Italy

    Active - Recruiting

  • Section Anaesthesia Analgesia and Intensive Care, Department of Medicine and Surgery: UNIVERSITA DEGLI STUDI DI PERUGIA

    Perugia,
    Italy

    Site Not Available

  • UOC di Anestesia e Rianimazione Cardio Toraco Vascolare dell'AOU San Giovanni di Dio e Ruggi d'Aragona "Scuola Medica Salernitana", Salerno University Hospital

    Salerno,
    Italy

    Active - Recruiting

  • S.C. Anestesia - Rianimazione Azienda Ospedaliera Santa Maria - Terni

    Terni,
    Italy

    Active - Recruiting

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