The 90% Minimum Effective Concentration of Bupivacaine Liposomes for Preserving Motion Function

Last updated: January 13, 2025
Sponsor: Affiliated Hospital of Jiaxing University
Overall Status: Active - Recruiting

Phase

4

Condition

Vomiting

Treatment

First patient Bupivacaine liposome and next patient Bupivacaine liposome

Next patients Bupivacaine liposome

First patient Bupivacaine liposome

Clinical Study ID

NCT06587386
2024-KY-656
  • Ages 41-65
  • All Genders

Study Summary

Explore the 90% minimum effective concentration of bupivacaine liposomes for preserving motor function.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Age 41-65 years ASA physical condition 1-2 BMI 18-30 kg/m2 undergoing arthroscopic shoulder surgery

Exclusion

Exclusion Criteria:

Inability to consent to the study pregnancy allergy to local anesthetics preexisting neuropathy cervical pathologies (i.e., herniated disc, myelopathy) chronic pain syndromes (defined as reflex sympathetic dystrophy or complex regional pain syndrome) severe respiratory conditions psychiatric or cognitive disorders that prohibit patients from adhering to the study protocol history of drug or alcohol abuse chronic opioid use (longer than 3 months or daily morphine equivalents more than 5mg/day for 1 month) contraindication for general anesthesia and/or interscalene nerve block and planned open shoulder arthrotomies Muscle related diseases

Study Design

Total Participants: 54
Treatment Group(s): 3
Primary Treatment: First patient Bupivacaine liposome and next patient Bupivacaine liposome
Phase: 4
Study Start date:
September 07, 2024
Estimated Completion Date:
March 01, 2025

Study Description

Our research group plans to conduct a dose exploration experiment, using a biased coin design sequential method to explore the 90% minimum effective concentration of bupivacaine liposomes for preserving motor function after intermuscular groove brachial plexus block surgery in shoulder arthroscopy.

Connect with a study center

  • Affiliated Hospital of Jiaxing University

    Jiaxing,
    China

    Active - Recruiting

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