Thailand Transgender Women Stigma Study

Last updated: March 29, 2025
Sponsor: University of Massachusetts, Worcester
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Standard PrEP Counseling

Finding Respect and Ending Stigma around HIV (FRESH)

Mobile Healthy Choices (mHC)

Clinical Study ID

NCT06576648
STUDY00001982
R34MH134682-01A1
  • Ages 18-29
  • Male
  • Accepts Healthy Volunteers

Study Summary

This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-negative Thai, young transgender women (18-29 years).

Eligibility Criteria

Inclusion

Aim 1 (Formative Research and Beta-Testing) Transgender women

Inclusion Criteria:

  • Ages between 18 and 29 years

  • Male sex at birth

  • Self-identifies as women, transgender women or culturally identifies with the femalespectrum

  • Laboratory-confirmed HIV-negative status

  • Self-reported recent history of condomless sex

  • Able to understand, read and speak Thai

  • Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills/week)in the past month.

Exclusion

Exclusion Criteria:

  • Have a serious cognitive or psychiatric problem compromising ability to provideinformed consent

  • Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)

  • Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreasedcreatinine clearance)

  • Currently enrolled in another HIV intervention study.

Healthcare providers Inclusion criteria

  • Age 18 or above

  • Has provided HIV prevention or treatment services for TGW for at least one yearExclusion criteria

  • None

Aim 2 (Pilot RCT) Transgender women Inclusion criteria

  • Ages between 18 and 29 years

  • Male sex at birth

  • Self-identifies as women, transgender women or culturally identifies with the femalespectrum

  • Laboratory-confirmed HIV-negative status

  • Self-reported recent history of condomless sex

  • Able to understand, read and speak Thai

  • Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills/week)in the past month.

Exclusion criteria

  • Have a serious cognitive or psychiatric problem compromising ability to provideinformed consent

  • Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)

  • Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreasedcreatinine clearance)

  • Currently enrolled in another HIV intervention study.

Study Design

Total Participants: 154
Treatment Group(s): 3
Primary Treatment: Standard PrEP Counseling
Phase:
Study Start date:
February 20, 2025
Estimated Completion Date:
August 14, 2027

Connect with a study center

  • Institute of HIV Research and Innovation

    Bangkok,
    Thailand

    Active - Recruiting

  • Rainbow Sky Association of Thailand

    Bangkok,
    Thailand

    Active - Recruiting

  • SWING Foundation

    Bangkok,
    Thailand

    Active - Recruiting

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