Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates

Last updated: August 24, 2024
Sponsor: College of Physicians and Surgeons Pakistan
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Umblical Cord Clamping

Clinical Study ID

NCT06573333
369452
  • Ages 1-6
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Title: Effect of timing of cord clamping of serum calcium levels in neonates Background: Hypocalcemia is a common metabolic problem in neonatal period. Most cases of hypocalcemia are asymptomatic however, the symptomatic cases require prompt management.

Objective: The objective is to determine the effects of early and delayed cord on serum calcium level in neonates Study Design: Randomized Controlled Trial

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Neonates born at gestational age 37 weeks to 41 weeks with no maternal complication.Parents who give consent for inclusion in the study

Exclusion

Exclusion Criteria:

  • Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension).Babies with congenital malformations and intrauterine growth restriction.

Study Design

Total Participants: 200
Treatment Group(s): 1
Primary Treatment: Umblical Cord Clamping
Phase:
Study Start date:
January 01, 2024
Estimated Completion Date:
September 30, 2024

Study Description

Place and Duration of Study: PEMH Rawalpindi and CMH Rawalpindi from January 2024 to July 2024.

Patients and Methods: Total sample size of 200 neonates will be included in the study divided into four groups with cord clamping at 15s, 30s, 60s, 120s each group will have a total of 50 neonates. Blood sampling for CBC / CRP / S. Electrolytes (Na, K, Total Ca, Ionized Ca, Mg), S Calcitonin, ABGs (HCO3 Levels) samples will be collected at 6 hours of life.

  • Inclusion Criteria: Neonates born at gestational age 37 weeks to 41 weeks with no maternal complication. Parents who give consent for inclusion in the study

  • Exclusion Criteria: Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension). Babies with congenital malformations and intrauterine growth restriction.

Expected Results: Research data on serum Calcium levels in neonates have shown no correlation to timing of cord clamping. Same results are expected in this study.

Connect with a study center

  • Pak Emirates Military Hospital

    Rawalpindi, Punjab 45000
    Pakistan

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.