BFR Training on Muscle Morphology

Last updated: June 27, 2025
Sponsor: Udayana University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Sham Low load-BFRt

High load-Eccentric training

Low load-BFRt

Clinical Study ID

NCT06566950
1791/UN14.2.2.VII.14/LT.2024
  • Ages 15-35
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This randomized clinical trial study compares high-load eccentric training (HL-Et), sham LL-BFRt, and low-load blood flow restriction (LL-BFRt) in sportsmen. The primary inquiries it seeks to address are:

Is LL-BFR superior to HL-Et and sham LL-BFRt in terms of improving muscle morphology? Is LL-BFR a more effective Patellofemoral Pain Syndrome and ACL injury preventive than HL-Et and sham LL-BFRt?

The three intervention groups that will be randomly assigned to participants are LL-BFRt, sham LL-BFRt, and HL-Et. Participants are expected to carry out:

Participants in LL-BFRt will be required to perform LL eccentric training at 30% of their repetition maximum (RM) and 70% of their artery occlusion pressure (AOP). This training will include stairs, single leg squat, and single leg deadlift.

Participants in HL-Et will be required to perform LL eccentric training at 70% of their maximum number of repetitions (RM).

In order to determine whether muscular morphology and the prevention of Patellofemoral Pain Syndrome and ACL injury improve following the interventions and follow-up, researchers will compare LL-BFRt, sham LL-BFRt, and HL-Et.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Being between the ages of 15 and 35

  • Play level 1 sports (fight martial arts, basketball, futsal, and soccer) at leasttwice a week

  • Never experienced an Patellofemoral Pain Syndrome or ACL injury before

  • Never experienced a grade III sprain or strain

  • Consent to participate in the study until its conclusion and provide informedconsent.

Exclusion

Exclusion Criteria:

  • Having a tumor, cancer, vena thromboembolic disease, obesity, diabetes,hypertension, anemia, and renal failure

  • Disabilities or those who are disabled.

Study Design

Total Participants: 75
Treatment Group(s): 3
Primary Treatment: Sham Low load-BFRt
Phase:
Study Start date:
September 20, 2024
Estimated Completion Date:
November 20, 2025

Connect with a study center

  • Physical therapy laboratory, College of Medicine, Universitas Udayana and ROM Physiotherapy Private Clinic Denpasar

    Denpasar, Bali 80232
    Indonesia

    Active - Recruiting

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